hurricane helene

two-men-fell-gravely-ill-last-year;-their-infections-link-to-deaths-in-the-’80s

Two men fell gravely ill last year; their infections link to deaths in the ’80s

CDC, Georgia, health, hurricane helene, Infectious disease, melioidosis, soil bacterium / /

Doctors soon discovered they were infected with the rare soil bacterium, which causes a disease called melioidosis.

Dangerous infection

Generally, melioidosis can be difficult to diagnose and tricky to treat, as it is naturally resistant to some antibiotics. It can infect people if they breathe it in or get it into open cuts. Sometimes the infection can stay localized, like a lung infection or a skin ulcer. But it can also get into the blood and become a systemic infection, spreading to various organs, including the brain. Fatality rates can be as high as 90 percent in people who are not treated but fall to less than 40 percent in people who receive prompt, proper care.

Both men in 2024 were quickly hospitalized and diagnosed with sepsis. Both were treated with heavy antibiotic regimens and recovered, though patient 2 relapsed in November, requiring another hospital stay. He ultimately recovered again.

According to the CDC, about a dozen melioidosis cases are identified each year in the US on average, but most occur in people who have traveled to areas known to harbor the bacterium. Neither of the men infected last year had recently traveled to any such places. So the researchers turned to genetic sequencing, which revealed the link to two cases in the 1980s.

In those cases, both men died from the infection. The man dubbed Patient 3 died in October of 1989. He was a veteran who fought in Vietnam—where the bacterium is endemic—two decades prior to his infection. The researchers note that such a long latency period for a B. pseudomallei infection is not entirely out of the question, but it would be rare to have such a large gap between an exposure and an infection. More suspiciously, the researchers note that in the month prior to Patient 3’s death, Hurricane Hugo made landfall in Georgia as a Category 4 storm, dumping three to five inches of rain.

Two men fell gravely ill last year; their infections link to deaths in the ’80s Read More »

america’s-fragile-drug-supply-chain-is-extremely-vulnerable-to-climate-change

America’s fragile drug supply chain is extremely vulnerable to climate change

health, hurricane helene, medical supply chain, natural disaster, supply chain shortages, supply chains / /

Vulnerabilities

Using data from the Food and Drug Administration, the researchers identified 10,861 drug facilities that were active for at least one year between 2019 and 2024. These facilities represent the array of manufacturing stages of a drug, from analyzing raw drug materials, to manufacturing active ingredients, to packaging drug products. The researchers then looked at the county location of each of these facilities and whether any federally declared weather emergencies occurred in those counties during the period. Weather-related emergencies included those from fires, hurricanes, storms, tornadoes, and floods.

During the six-year span, 6,819 facilities (63 percent) faced at least one weather-related emergency. Per year, an average of 2,146 facilities (33 percent) experienced such an emergency.

The researchers noted that there was no statistically significant difference in the likelihood that counties with or without a drug facility would experience a weather-related emergency. That is, it’s not the case that drug facilities have been built in areas uniquely vulnerable to climate-related disasters.

Still, with a third of US facilities at risk of weather disasters each year, the study clearly shows how fraught it is to have flimsy supply chains—like having a single plant produce 60 percent of the country’s supply of an essential drug product.

“These findings underscore the importance of recognizing climate-related vulnerabilities and the urgent need for supply chain transparency, for strategic allocation of production, and for disaster risk management strategies to prevent health care disruptions in the US,” the authors conclude.

America’s fragile drug supply chain is extremely vulnerable to climate change Read More »

as-hospitals-struggle-with-iv-fluid-shortage,-nc-plant-restarts-production

As hospitals struggle with IV fluid shortage, NC plant restarts production

baxter, drugs, Fluid, health, hospitals, hurricane helene, iV, North Carolina, Science, shortage / /

The western North Carolina plant that makes 60 percent of the country’s intravenous fluid supply has restarted its highest-producing manufacturing line after being ravaged by flooding brought by Hurricane Helene last month.

While it’s an encouraging sign of recovery as hospitals nationwide struggle with shortages of fluids, supply is still likely to remain tight for the coming weeks.

IV fluid maker Baxter Inc, which runs the Marion plant inundated by Helene, said Thursday that the restarted production line could produce, at peak, 25 percent of the plant’s total production and about 50 percent of the plant’s production of one-liter IV solutions, the product most commonly used by hospitals and clinics.

“Recovery progress at our North Cove site continues to be very encouraging,” Baxter CEO and President José Almeida said. “In a matter of weeks, our team has advanced from the depths of Hurricane Helene’s impact to restarting our highest-throughput manufacturing line. This is a pivotal milestone, but more hard work remains as we work to return the plant to full production.”

Overall, Baxter said it is ahead of its previously projected timeline for getting the massive plant back up and running. Previously, the company said it had aimed to produce 90–100 percent of some products by the end of the year. Still, the initial batches now under production are expected to start shipping in late November at the earliest.

One of the many challenges to restoring the facility was the lack of access to the site; Helene had damaged an access bridge. In its latest announcement, Baxter said that a temporary bridge—built with support from North Carolina’s Department of Transportation and the federal Administration of Strategic Preparedness and Response (ASPR)—has allowed the transport of more than 885 truckloads of existing inventory out of the plant since Helene.  A second temporary bridge, expected to be completed in early November, will enable further access of traffic and equipment to the site.

As hospitals struggle with IV fluid shortage, NC plant restarts production Read More »

rapid-analysis-finds-climate-change’s-fingerprint-on-hurricane-helene

Rapid analysis finds climate change’s fingerprint on Hurricane Helene

atmospheric science, climate change, Earth science, hurricane helene, hurricanes, meteorology, Rainfall, Science / /

The researchers identified two distinct events associated with Helene’s landfall. The first was its actual landfall along the Florida coast. The second was the intense rainfall on the North Carolina/Tennessee border. This rainfall came against a backdrop of previous heavy rain caused by a stalled cold front meeting moisture brought north by the fringes of the hurricane. These two regions were examined separately.

A changed climate

In these two regions, the influence of climate change is estimated to have caused a 10 percent increase in the intensity of the rainfall. That may not seem like much, but it adds up. Over both a two- and three-day window centered on the point of maximal rainfall, climate change is estimated to have increased rainfall along the Florida Coast by 40 percent. For the southern Appalachians, the boost in rainfall is estimated to have been 70 percent.

The probability of storms with the wind intensity of Helene hitting land near where it did is about a once-in-130-year event in the IRIS dataset. Climate change has altered that so it’s now expected to return about once every 50 years. The high sea surface temperatures that helped fuel Helene are estimated to have been made as much as 500 times more likely by our changed climate.

Overall, the researchers estimate that rain events like Helene’s landfall should now be expected about once every seven years, although the uncertainty is large (running from three to 25 years). For the Appalachian region, where rainfall events this severe don’t appear in our records, they are likely to now be a once-in-every-70-years event thanks to climate warming (with an uncertainty of between 20 and 3,000 years).

“Together, these findings show that climate change is enhancing conditions conducive to the most powerful hurricanes like Helene, with more intense rainfall totals and wind speeds,” the researchers behind the work conclude.

Rapid analysis finds climate change’s fingerprint on Hurricane Helene Read More »