health

bird-flu-jumps-from-birds-to-human-in-louisiana;-patient-hospitalized

Bird flu jumps from birds to human in Louisiana; patient hospitalized

A person in Louisiana is hospitalized with H5N1 bird flu after having contact with sick and dying birds suspected of carrying the virus, state health officials announced Friday.

It is the first human H5N1 case detected in Louisiana. For now, the case is considered a “presumptive” positive until testing is confirmed by the Centers for Disease Control and Prevention. Health officials say that the risk to the public is low but caution people to stay away from any sick or dead birds.

Although the person has been hospitalized, their condition was not immediately reported. It’s also unclear what kind of birds the person had contact with—wild, backyard, or commercial birds. Ars has reached out to Louisiana’s health department and will update this piece with any additional information.

The case is just the latest amid H5N1’s global and domestic rampage. The virus has been ravaging birds of all sorts in the US since early 2022 and spilling over to a surprisingly wide range of mammals. In March this year, officials detected an unprecedented leap to dairy cows, which has since caused a nationwide outbreak. The virus is currently sweeping through California, the country’s largest dairy producer.

To date, at least 845 herds across 16 states have contracted the virus since March, including 630 in California, which detected its first dairy infections in late August.

Human cases

At least 60 people in the US have been infected amid the viral spread this year. But the new case in Louisiana stands out. To date, nearly all of the human cases have been among poultry and dairy workers—unlike the new case in Louisiana— and almost all have been mild—also unlike the new case. Most of the cases have involved conjunctivitis—pink eye—and/or mild respiratory and flu-like symptoms.

There was a case in a patient in Missouri who was hospitalized. However, that person had underlying health conditions, and it’s unclear if H5N1 was the cause of their hospitalization or merely an incidental finding. It remains unknown how the person contracted the virus. An extensive investigation found no animal or other exposure that could explain the infection.

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americans-spend-more-years-being-unhealthy-than-people-in-any-other-country

Americans spend more years being unhealthy than people in any other country

For the new study, researchers at the Mayo Clinic analyzed health statistics collected by the World Health Organization. The resource included data from 183 countries, allowing the researchers to compare countries’ life expectancy and healthspans, which are calculated by years of life weighted by health status.

Longer, but not better

Overall, the researchers saw lifespan-healthspan gaps grow around the world, with the average gap rising from 8.5 years in 2000 to 9.6 years in 2019. Global life expectancy rose 6.5 years, to about 73 years, while healthspans only rose 5.4 years in that time, to around 63 years.

But the US was a notable outlier, with its gap growing from 10.9 years to 12.4 years, a 29 percent higher gap than the global mean.

The gap was most notable for women—a trend seen around the world. Between 2000 and 2019, US women saw their life expectancy rise 1.5 years, from 79.2 to 80.7 years, but they saw no change in their healthspans. Women’s lifespan-healthspan gap rose from 12.2 years to 13.7 years. For US men, life expectancy rose 2.2 years, from 74.1 to 76.3 years, and their healthspans also increased 0.6 years. Their lifespan-healthspan gap in 2019 was 11.1 years, 2.6 years shorter than women’s.

The conditions most responsible for US disease burden included mental and substance use disorders, plus musculoskeletal diseases. For women, the biggest contributors were musculoskeletal, genitourinary, and neurological diseases.

While the US presented the most extreme example, the researchers note that the global trends seem to present a “disease paradox whereby reduced acute mortality exposes survivors to an increased burden of chronic disease.”

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avian-flu-cases-are-on-the-upswing-at-big-dairy-farms

Avian flu cases are on the upswing at big dairy farms


Rise in cases amplifies concerns about consolidation in agriculture.

Holstein dairy cows in a freestall barn. Credit: Getty |

A handful of dairy farms sprawl across the valley floor, ringed by the spikey, copper-colored San Jacinto mountains. This is the very edge of California’s dairy country—and so far, the cows here are safe.

But everyone worries that the potentially lethal bird flu is on the way. “I hope not,” says Clemente Jimenez, as he fixes a hose at Pastime Lakes, a 1,500-head dairy farm. “It’s a lot of trouble.”

Further north and west, in the San Joaquin Valley—the heart of the state’s dairy industry—the H5N1 virus, commonly known as bird flu, has rippled through the massive herds that provide most of the country’s milk. Farmworkers have piled carcasses into black and white heaps. This week the state reported 19 new confirmed cases in cows and more than 240,000 in chickens. Another 50,000 cases were confirmed at a chicken breeding facility in Oklahoma.

Most worrying, though, is the spillover from livestock to humans. So far, 58 people in the United States have tested positive for bird flu. Fifty-six of them worked either on dairy or poultry farms where millions of birds had to be culled.

The Centers for Disease Control and Prevention confirmed that four of the cases in humans had no known connection to livestock, raising fears that the virus eventually could jump from one human to another, though that hasn’t happened yet. On Thursday, a study published in Science by researchers at The Scripps Research Institute said it would take only a single mutation in the H5N1 virus for it to attach itself to human receptor cells.

Large livestock facilities in states across the country, and especially in California, have become the epicenters of these cases, and some researchers say that’s no surprise: Putting thousands, even hundreds of thousands, of animals together in confined, cramped barns or corrals creates a petri dish for viruses to spread, especially between genetically similar and often stressed animals.

More drought and higher temperatures, fueled by climate change, supercharge those conditions.

“Animal production acts like a connectivity for the virus,” said Paula Ribeiro Prist, a conservation scientist with the EcoHealth Alliance, a not-for-profit group that focuses on research into pandemics. “If you have a lot of cattle being produced in more places, you have a higher chance of the virus spreading. When you have heat stress, they’re more vulnerable.”

So far, this bird flu outbreak has affected more than 112 million chickens, turkeys, and other poultry across the US since it was first detected at a turkey-producing facility in Indiana in February 2022. In March of this year, officials confirmed a case of the virus in a Texas dairy cow—the first evidence that the virus had jumped from one livestock species to another. Since then, 720 cows have been affected, most of them in California, where there have been nearly 500 recorded cases.

In the United States, a trend of consolidation in agriculture, particularly dairies, has seen more animals housed together on ever-larger farms as the number of small farms has rapidly shrunk. In 1987, half of the country’s dairy cows were in herds of 80 or more, and half in herds of 80 or fewer. Twenty years later, half the country’s cows were raised in herds of 1,300 or more. Today, 5,000-head dairies are common, especially in the arid West.

California had just over 21,000 dairy farms in 1950, producing 5.6 billion pounds of milk. Today, it has 1,100 producing around 41 billion pounds. Total US milk production has soared from about 116 billion pounds in 1950 to about 226 billion today.

“The pace of consolidation in dairy far exceeds the pace of consolidation seen in most of US agriculture,” a recent USDA report said.

Initially, researchers thought the virus was spreading through cows’ respiration, but recent research suggests it’s being transmitted through milking equipment and milk itself.

“It’s been the same strain in dairy cows… We don’t necessarily have multiple events of spillover,” said Meghan Davis, an associate professor of environmental health and engineering at Johns Hopkins Bloomberg School of Public Health. “Now it’s transmission from one cow to the next, often through milking equipment.”

It’s still unclear what caused that initial jump from wild birds, which are the natural reservoirs of the virus, to commercial poultry flocks and then to cows, but some research suggests that changing migration patterns caused by warmer weather are creating conditions conducive to the spreading of viruses. Some wild birds are migrating earlier than usual, hatching juvenile birds in new or different habitats.

“This is leading to a higher number of young that are naive to the virus,” Prist explained. “This makes the young birds more infectious—they have a higher chance of transmitting the virus because they don’t have antibodies protecting them.

“They’re going to different areas and they’re staying longer,” Prist added, “so they have higher contact with other animals, to the other native populations, that they have never had contact [with] before.”

That, researchers believe, could have initiated the spillover from wild birds to poultry, where it has become especially virulent. In wild birds, the virus tends to be a low pathogenic strain that occurs naturally, causing only minor symptoms in some birds.

“But when we introduce the virus to poultry operations where birds live in unsanitary and highly confined conditions, the virus is … able to spread through them like wildfire,” said Ben Rankin, a legal expert with the Center for Biological Diversity, an advocacy group. “There are so many more opportunities for the virus to mutate, to adapt to new kinds of hosts, and eventually, the virus spills back into the wild and this creates this cycle, or this loop, of intensification and increasing pathogenicity.”

Rankin pointed to an analysis that looked at 39 different viral outbreaks in birds from 1959 to 2015, where a low pathogenic avian influenza became a highly pathogenic one. Out of those, 37 were associated with commercial poultry operations. “So it’s a very clear relationship between the increasing pathogenicity of this virus and its relationship with industrial animal raising,” Rankin said.

Some researchers worry that large farms with multiple species are providing the optimal conditions for more species-to-species transfer. In North Carolina, the second-largest hog-producing state after Iowa, some farmers have started raising both chickens and hogs under contracts that require huge numbers of animals.

“So you’ve got co-location at a pretty substantial scale of herd size, on a single property,” said Chris Heaney, an associate professor of environmental health, engineering, epidemiology, and international health at the Bloomberg School of Public Health. “Another concern is seeing it jump into swine. That host, in particular, is uniquely well suited for those influenza viruses to re-assort and acquire properties that are very beneficial for taking up residence in humans.”

In late October, the USDA reported the first case of bird flu in a pig that lived on a small poultry and hog farm in Oregon.

Farmworker advocates say the number of cases in humans is likely underreported, largely because the immigrant and non-English speaking workforce on farms could be reluctant to seek help or may not be informed about taking precautions.

“What we’re dealing with is the lack of information from the top to the workers,” said Ana Schultz, a director with Project Protect Food Systems Workers.

In northern Colorado, home to dozens of large dairies, Schultz started to ask dairy workers in May if they were getting protective gear and whether anyone was falling ill. Many workers told her they were feeling flu-ish but didn’t go to the doctor for fear of losing a day of work or getting fired.

“I feel like there’s a lot more avian flu incidents, but no one knows about it because they don’t go to the doctor and they don’t get tested,” Schultz said. “In all the months that we’ve been doing outreach and taking protective gear and flyers, we haven’t had one single person tell us they’ve been to the doctor.”

This story originally appeared on Inside Climate News.

Georgina Gustin covers agriculture for Inside Climate News and has reported on the intersections of farming, food systems, and the environment for much of her journalism career. Her work has won numerous awards, including the John B. Oakes Award for Distinguished Environmental Journalism, and she was twice named the Glenn Cunningham Agricultural Journalist of the Year, once with ICN colleagues. She has worked as a reporter for The Day in New London, Conn., the St. Louis Post-Dispatch and CQ Roll Call, and her stories have appeared in The New York Times, Washington Post, and National Geographic’s The Plate, among others. She is a graduate of the Columbia University Graduate School of Journalism and the University of Colorado at Boulder.

Photo of Inside Climate News

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us-to-start-nationwide-testing-for-h5n1-flu-virus-in-milk-supply

US to start nationwide testing for H5N1 flu virus in milk supply

So, the ultimate goal of the USDA is to eliminate cattle as a reservoir. When the Agency announced it was planning for this program, it noted that there were two candidate vaccines in trials. Until those are validated, it plans to use the standard playbook for handling emerging infections: contact tracing and isolation. And it has the ability to compel cattle and their owners to be more cooperative than the human population turned out to be.

The five-step plan

The USDA refers to isolation and contact tracing as Stage 3 of a five-stage plan for controlling H5N1 in cattle, with the two earlier stages being the mandatory sampling and testing, meant to be handled on a state-by-state basis. Following the successful containment of the virus in a state, the USDA will move on to batch sampling to ensure each state remains virus-free. This is essential, given that we don’t have a clear picture of how many times the virus has jumped from its normal reservoir in birds into the cattle population.

That makes it possible that reaching Stage 5, which the USDA terms “Demonstrating Freedom from H5 in US Dairy Cattle,” will turn out to be impossible. Dairy cattle are likely to have daily contact with birds, and it may be that the virus will be regularly re-introduced into the population, leaving containment as the only option until the vaccines are ready.

Testing will initially focus primarily on states where cattle-to-human transmission is known to have occurred or the virus is known to be present: California, Colorado, Michigan, Mississippi, Oregon, and Pennsylvania. If you wish to track the progress of the USDA’s efforts, it will be posting weekly updates.

US to start nationwide testing for H5N1 flu virus in milk supply Read More »

splash-pads-really-are-fountains-of-fecal-material;-cdc-reports-10k-illnesses

Splash pads really are fountains of fecal material; CDC reports 10K illnesses

Once infectious material gets into the water, disinfection systems that aren’t working properly or are inadequate can allow pathogens to gush from every nozzle. Splash pads aren’t unique in having to handle sick children in poopy swim diapers—but they are unique in how they are regulated. That is, in some places, they’re not regulated at all. Splash pads are designed to not have standing water, therefore reducing the risk of young children drowning. But, because they lack standing water, they are sometimes deemed exempt from local health regulations. Before 2000, only 13 states regulated splash pads. Though many states have since added regulations, some did so only after splash pad-linked outbreaks were reported.

Downpour of disease

The primary method for keeping recreational water free of infectious viruses and bacteria is chlorinating it. However, maintaining germ-killing chlorine concentration is especially difficult for splash pads because the jets and sprays aerosolize chlorine, lowering the concentration.

Still, in most splash-pad linked outbreaks, standard chlorine concentrations aren’t enough anyway. The most common pathogen to cause an outbreak at splash pads is the parasite Cryptosporidium, aka Crypto. The parasite’s hardy spores, called oocysts, are extremely tolerant of chlorine, surviving in water with the standard chlorine concentration (1 ppm free chlorine) for over seven days. (Other germs die in minutes.) In splash pads that might not even have that standard chlorine concentration, Crypto flourishes and can cause massive outbreaks.

In 2023, the CDC recommended new health codes that call for “secondary disinfection” methods to keep Crypto at bay, including disinfection systems using ozone or ultraviolet light. Another possible solution is to have “single-pass” splash pads that don’t recirculate water.

In all, to keep splash pads from being geysers of gastrointestinal parasites and pathogens, various changes have to happen, the CDC experts say.

“Prevention of waterborne disease outbreaks at splash pads requires changes in user behavior; recreational venue code updates; and improved venue design, construction, operation, and management of facilities,” they conclude. But it should all start with keeping kids from sitting on jets and drinking the water.

Splash pads really are fountains of fecal material; CDC reports 10K illnesses Read More »

man-suffers-chemical-burn-that-lasted-months-after-squeezing-limes

Man suffers chemical burn that lasted months after squeezing limes

If Margaritaville were a real place, it should definitely keep a few dermatologists on hand.

In a case of an oft-overlooked food preparation risk, a 40-year-old man showed up to an allergy clinic in Texas with a severe, burning rash on both his hands that had two days earlier. A couple of days later, it blistered. And a few weeks after that, the skin darkened and scaled. After several months, the skin on his hands finally returned to normal.

The culprit: lime juice and sunlight.

It turns out that just before developing the nasty skin eruption, the man had manually squeezed a dozen limes, then headed to an outdoor soccer game without applying sunscreen. His doctors diagnosed the man’s rash as a classic case of phytophotodermatitis, according to a case report published Wednesday in the New England Journal of Medicine.

The condition is caused by toxic substances found in plants (phyto) that react with UV light (photo) to cause a burning, blistering, scaling, pigmented skin condition (dermatitis).

Specifically, the toxic chemicals are furocoumarins, which are found in some weeds and also a range of plants used in food. Those include celery, carrot, parsley, fennel, parsnip, lime, bitter orange, lemon, grapefruit, and sweet orange. Furocoumarins include chemicals with linear structures, psoralens, and angular structures, called angelicins, though not all of them are toxic.

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biased-ai-in-health-care-faces-crackdown-in-sweeping-biden-admin-proposals

Biased AI in health care faces crackdown in sweeping Biden admin proposals

Prior authorization

Elsewhere in the over 700-page proposal, the administration lays out policy that would bar Medicare Advantage plan providers from reopening and reneging on paying claims for inpatient hospital admission if those claims had already been granted approval through prior authorization. The proposal also wants to make criteria for coverage clearer and help ensure that patients know they can appeal denied claims.

The Department of Health and Human Services notes that when patients appeal claim denials from Medicare Advantage plans, the appeals are successful 80 percent of the time. But, only 4 percent of claim denials are appealed—”meaning many more denials could potentially be overturned by the plan if they were appealed.”

AI guardrails

Last, the administration’s proposal also tries to shore up guardrails for the use of AI in health care with edits to existing policy. The goal is to make sure Medicare Advantage insurers don’t adopt flawed AI recommendations that deepen bias and discrimination or exacerbate existing inequities.

As an example, the administration pointed to the use of AI to predict which patients would miss medical appointments—and then recommend that providers double-book the appointment slots for those patients. In this case, low-income patients are more likely to miss appointments, because they may struggle with transportation, childcare, and work schedules. “As a result of using this data within the AI tool, providers double-booked lower-income patients, causing longer wait times for lower-income patients and perpetuating the cycle of additional missed appointments for vulnerable patients.” As such, it should be barred, the administration says.

In general, people of color and people of lower socioeconomic status tend to be more likely to have gaps and flaws in their electronic health records. So, when AI is trained on large data sets of health records, it can generate flawed recommendations based on that spotty and incorrect information, thereby amplifying bias.

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things-aren’t-looking-good-for-infamous-ceo-of-“health-care-terrorists”

Things aren’t looking good for infamous CEO of “health care terrorists”

Earlier this year, a Maltese magistrate concluded a four-year investigation into the matter and recommended that Ernst and de la Torre be charged with money laundering, criminal association, and corruption of public officials, including the nation’s former prime minister, Joseph Muscat, the Globe reports.

Meanwhile, new allegations of domestic dealings continue to come to light. In a separate investigative story Monday, the Globe reported that Steward executives used Steward-owned malpractice insurer TRACO “like a piggy bank.” The Panama-based TRACO was supposed to work like an independent insurer for the hospital chain; Steward would pay TRACO malpractice insurance premiums on behalf of its doctors and the pooled money would be used to litigate and pay out claims. But, instead of paying premiums, Steward gave TRACO IOUs. By the end of 2023, TRACO’s accounting records showed $99 million in outstanding loans, most owed by Steward, and $176 million in “accounts receivable,” also mostly owed by Steward.

With Steward now in bankruptcy, insurance coverage for health care providers is now in question, as are payouts to patients who were harmed by Steward’s care. The Globe noted the case of Yasmany Sosa, whose 35-year-old wife, Yanisey Rodriguez, died a preventable death after giving birth at Steward North Shore Medical Center in Florida in September 2022. Steward agreed to a $4 million settlement with Sosa in March, but the money hasn’t appeared, leaving Sosa in limbo and struggling.

“They killed my wife, that’s for starters. Second of all, they destroyed my family,” Sosa told the Globe through a translator. “This has all become a bunch of loopholes, legal strategies. This really is very difficult for me… I’ve already lost everything.”

Things aren’t looking good for infamous CEO of “health care terrorists” Read More »

raw-milk-recalled-for-containing-bird-flu-virus,-california-reports

Raw milk recalled for containing bird flu virus, California reports

Pasteurization

The milk-related risk of H5N1 is only from raw milk; pasteurized milk does not contain live virus and is safe to drink. Pasteurization, which heats milk to a specific temperature for a specified amount of time, kills a variety of bacteria and viruses, including bird flu. Influenza viruses, generally, are considered susceptible to heat treatments because they have an outer layer called an envelope, which can be destabilized by heat. Studies that have specifically looked at the effectiveness of heat-killing treatments against H5N1 have repeatedly found that pasteurization effectively inactivates the virus.

The advent of pasteurization is considered a public health triumph. Its adoption of a safe milk supply contributed to a dramatic reduction in infant deaths in the early 20th century. Before that, milkborne infections—including human and bovine tuberculosis, brucellosis, salmonellosis, streptococcal infections, diphtheria, and “summer diarrhea”—were common killers of infants.

As such, public health officials have long advised people against consuming raw milk, which has no evidence-based health benefits. Raw milk consumption, meanwhile, is linked to higher rates of outbreaks from pathogens including Salmonella, Listeria monocytogenes, toxin-producing E. coli, Brucella, Campylobacter, and many other bacteria.

Risky drinking

Since H5N1 was found spreading among dairy cows in March, health experts have warned about the additional risk of consuming raw milk. Still, consumption of raw milk has continued, and surprisingly increased, as supporters of the dangerous practice have accused health officials of “fearmongering.”

When the retail sampling of Raw Farm’s milk came back positive, the California Department of Food and Agriculture (CDFA) conducted testing at the company’s locations, which were negative for the virus. The CDFA will now begin testing Raw Farm’s milk for bird flu twice a week.

The recalled milk has lot code 20241109 and a “best by” date of November 27, 2024, printed on the packaging.​

“Drinking or accidentally inhaling raw milk containing bird flu virus may lead to illness,” California’s public health department said. “In addition, touching your eyes, nose, or mouth with unwashed hands after touching raw milk with bird flu virus may also lead to infection.”

Some US dairy workers who contracted the virus from infected cows reported having had milk splash in their eyes and face. A common symptom of H5N1 infections in humans during the dairy outbreak has been conjunctivitis, aka eye inflammation.

Raw milk recalled for containing bird flu virus, California reports Read More »

surgeons-remove-2.5-inch-hairball-from-teen-with-rare-rapunzel-syndrome

Surgeons remove 2.5-inch hairball from teen with rare Rapunzel syndrome

Hair is resistant to digestion and isn’t easily moved through the digestive system. As such, it often gets lodged in folds of the gastric lining, denatures, and then traps food and gunk to form a mass. Over time, it will continue to collect material, growing into a thick, matted wad.

Of all the bezoars, trichobezoars are the most common. But none of them are particularly easy to spot. On CT scans, bezoars can be indistinguishable from food in the stomach unless there’s an oral contrast material. To look for a possible bezoar in the teen, her doctors ordered an esophagogastroduodenoscopy, in which a scope is put down into the stomach through the mouth. With that, they got a clear shot of the problem: a trichobezoar. (The image is here, but a warning: it’s graphic).

Tangled tail

But this trichobezoar was particularly rare; hair from the mottled mat had dangled down from the stomach and into the small bowel, which is an extremely uncommon condition called Rapunzel syndrome, named after the fairy-tale character who lets down her long hair. It carries a host of complications beyond acute abdominal pain, including perforation of the stomach and intestines, and acute pancreatitis. The only resolution is surgical removal. In the teen’s case, the trichobezoar came out during surgery using a gastrostomy tube. Surgeons recovered a hairball about 2.5 inches wide, along with the dangling hair that reached into the small intestine.

For any patient with a trichobezoar, the most important next step is to address any psychiatric disorders that might underlie hair-eating behavior. Hair eating is often linked to a condition called trichotillomania, a repetitive behavior disorder marked by hair pulling. Sometimes, the disorder can be diagnosed by signs of hair loss—bald patches, irritated scalp areas, or hair at different growth stages. But, for the most part, it’s an extremely difficult condition to diagnose as patients have substantial shame and embarrassment about the condition and will often go to great lengths to hide it.

Another possibility is that the teen had pica, a disorder marked by persistent eating of nonfood, nonnutritive substances. Intriguingly, the teen noted that she had pica as a toddler. But doctors were skeptical that pica could explain her condition given that hair was the only nonfood material in the bezoar.

The teen’s doctors would have liked to get to the bottom of her condition and referred her to a psychiatrist after she successfully recovered from surgery. But unfortunately, she did not return for follow-up care and told her doctors she would instead see a hypnotherapist that her friends recommended.

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trust-in-scientists-hasn’t-recovered-from-covid-some-humility-could-help.

Trust in scientists hasn’t recovered from COVID. Some humility could help.

Study 3 essentially replicated study 2, but with the tweak that the articles varied whether the fictional scientist was male or female, in case gendered expectations affected how people perceived humility and trustworthiness. The results from 369 participants indicated that gender didn’t affect the link between IH and trust. Similarly, in study 4, with 371 participants, the researchers varied the race/ethnicity of the scientist, finding again that the link between IH and trust remained.

“Together, these four studies offer compelling evidence that perceptions of scientists’ IH play an important role in both trust in scientists and willingness to follow their research-based recommendations,” the authors concluded.

Next steps

In the final study involving 679 participants, researchers examined different ways that scientists might express IH, including whether the IH was expressed as a personal trait, limitations of research methods, or as limitations of research results. Unexpectedly, the strategies to express IH by highlighting limitations in the methods and results of research both increased perceptions of IH, but shook trust in the research. Only personal IH successfully boosted perceptions of IH without backfiring, the authors report.

The finding suggests that more research is needed to guide scientists on how best to express high IH. But, it’s clear that low IH is not good. “[W]e encourage scientists to be particularly mindful of displaying low IH, such as by expressing overconfidence, being unwilling to course correct or disrespecting others’ views,” the researchers caution.

Overall, Schumann said she was encouraged by the team’s findings. “They suggest that the public understands that science isn’t about having all the answers; it’s about asking the right questions, admitting what we don’t yet understand, and learning as we go. Although we still have much to discover about how scientists can authentically convey intellectual humility, we now know people sense that a lack of intellectual humility undermines the very aspects of science that make it valuable and rigorous. This is a great place to build from.”

Trust in scientists hasn’t recovered from COVID. Some humility could help. Read More »

are-standing-desks-good-for-you?-the-answer-is-getting-clearer.

Are standing desks good for you? The answer is getting clearer.


Whatever your office setup, the most important thing is to move.

Without question, inactivity is bad for us. Prolonged sitting is consistently linked to higher risks of cardiovascular disease and death. The obvious response to this frightful fate is to not sit— move. Even a few moments of exercise can have benefits, studies suggest. But in our modern times, sitting is hard to avoid, especially at the office. This has led to a range of strategies to get ourselves up, including the rise of standing desks. If you have to be tethered to a desk, at least you can do it while on your feet, the thinking goes.

However, studies on whether standing desks are beneficial have been sparse and sometimes inconclusive. Further, prolonged standing can have its own risks, and data on work-related sitting has also been mixed. While the final verdict on standing desks is still unclear, two studies out this year offer some of the most nuanced evidence yet about the potential benefits and risks of working on your feet.

Take a seat

For years, studies have pointed to standing desks improving markers for cardiovascular and metabolic health, such as lipid levels, insulin resistance, and arterial flow-mediated dilation (the ability of arteries to widen in response to increased blood flow). But it’s unclear how significant those improvements are to averting bad health outcomes, such as heart attacks. One 2018 analysis suggested the benefits might be minor.

And there are fair reasons to be skeptical about standing desks. For one, standing—like sitting—is not moving. If a lack of movement and exercise is the root problem, standing still wouldn’t be a solution.

Yet, while sitting and standing can arguably be combined into the single category of ‘stationary,’ some researchers have argued that not all sitting is the same. In a 2018 position paper published in the Journal of Occupational and Environmental Medicine, two health experts argued that the link between poor health and sitting could come down to the specific populations being examined and “the special contribution” of “sitting time at home, for example, the ‘couch potato effect.'”

The two researchers—emeritus professors David Rempel, formerly at the University of California, San Francisco, and Niklas Krause, formerly of UC Los Angeles—pointed to several studies looking specifically at occupational sitting time and poor health outcomes, which have arrived at mixed results. For instance, a 2013 analysis did not find a link between sitting at work and cardiovascular disease. Though the study did suggest a link to mortality, the link was only among women. There was also a 2015 study on about 36,500 workers in Japan, who were followed for an average of 10 years. That study found that there was no link between mortality and sitting time among salaried workers, professionals, and people who worked at home businesses. However, there was a link between mortality and sitting among people who worked in farming, forestry, and fishing industries.

Still, despite some murkiness in the specifics, more recent studies continue to turn up a link between total prolonged sitting—wherever that sitting occurs—and poor health outcomes, particularly cardiovascular disease. This has kept up interest in standing desks in offices, where people don’t always have the luxury of frequent movement breaks. And this, in turn, has kept researchers on their toes to try to answer whether there is any benefit to standing desks.

One study published last month in the International Journal of Epidemiology offers a clearer picture of how standing desks may relate to cardiovascular health risks. The authors, an international team of researchers led by Matthew Ahmadi at the University of Sydney in Australia, found that standing desks don’t improve heart health—but they don’t harm it, either, whereas sitting desks do.

Mitigating risks

For the study, the researchers tracked the health data of a little over 83,000 people in the UK over an average of about seven years. During the study, participants wore a wrist-based accelerometer device for at least four days. The devices were calibrated to determine when they were sitting, standing, walking, or running during the waking hours. With that data, the researchers linked their sitting, standing, and stationary (combined sitting and standing) times to health outcomes in their medical records.

The researchers focused on two categories of health outcomes: cardiovascular, covering coronary heart disease, heart failure, and stroke; and orthostatic circulatory disease events, including orthostatic hypotension (blood pressure drops upon standing or sitting), varicose veins, chronic venous insufficiency (veins in your legs don’t move blood back up to your heart), and venous ulcers. The reasoning for this second category is that prolonged sitting and standing may pose risks for developing circulatory diseases.

The researchers found that when participants’ total stationary time (sitting and standing) went over 12 hours per day, risk of orthostatic circulatory disease increased 22 percent per additional hour, while risk of cardiovascular disease went up 13 percent per hour.

For just sitting, risks increased every hour after 10 hours: for orthostatic circulatory disease, risk went up 26 percent every hour after 10 hours, and cardiovascular disease risk went up 15 percent. For standing, risk of orthostatic circulatory disease went up after just two hours, increasing 11 percent every 30 minutes after two hours of standing. But standing had no impact on cardiovascular disease at any time point.

“Contrary to sitting time, more time spent standing was not associated with a higher CVD [cardiovascular disease] risk. Overall, there was no association for higher or lower CVD risk throughout the range of standing duration,” the authors report.

On the other hand, keeping sitting time under 10 hours and standing time under two hours was linked to a weak protective effect against orthostatic circulatory disease: A day of nine hours of sitting and 1.5 of standing (for a total of 11.5 hours of stationary time) lowered risk of orthostatic circulatory disease by a few percentage points, the study found.

In other words, as long as you can keep your total stationary time under 12 hours, you can use a little standing time help you keep your sitting time under 10 hours and avoid increasing both cardiovascular and orthostatic risks, according to the data.

Consistent finding

It’s a very detailed formula to reduce the health risks of long days at the office, but is it set in stone? Probably not. For one thing, it’s just one study that needs to be replicated in a different population. Also, the study didn’t look at any specifics of occupational versus leisure standing and sitting times, let alone the use of standing desks specifically. The study also based estimates of people’s sitting, standing, and total stationary time on as little as just four days of activity monitoring, which may or may not have been consistent over the nearly seven-year average follow-up period.

Still, the study’s takeaway generally fits with a study published in January in JAMA Network Open. This study looked at the link between occupational sitting time, leisure physical activity, and death rates—both deaths from all causes and those specifically caused by cardiovascular disease. Researchers used a group of over 480,000 workers in Taiwan, who were followed for an average of nearly 13 years.

The workers who reported mostly sitting at work had a 16 percent increased risk of all-cause mortality and a 34 percent higher risk of dying from cardiovascular disease compared with workers who did not sit at work. The workers who reported alternating between sitting and standing, meanwhile, did not have an increased risk of all-cause or cardiovascular disease mortality. The findings held after adjusting for health factors and looking at subgroups, including by sex, age, smokers, never-smokers, and people with chronic conditions.

That said, being highly active in leisure time appeared to offset the mortality risks among those who mostly sit at work. At the highest leisure-time activity levels reported, participants who mostly sit at work had comparable risks of all-cause mortality as those who alternated sitting and standing or were didn’t sit at work. Overall, the data suggested that keeping overall stationary time as low as possible and alternating sitting and standing to some extent at work can reduce risk.

The authors call for incorporating breaks in work settings and even specifically recommend allowing for standing and activity-permissive workstations.

The takeaway

While prolonged standing has its own risks, the use of standing desks at work can, to some extent, help lessen the risks of prolonged sitting. But, overall, it’s important to keep total stationary time as low as possible and exercise whenever possible.

Photo of Beth Mole

Beth is Ars Technica’s Senior Health Reporter. Beth has a Ph.D. in microbiology from the University of North Carolina at Chapel Hill and attended the Science Communication program at the University of California, Santa Cruz. She specializes in covering infectious diseases, public health, and microbes.

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