health

“red-meat-allergy”-from-tick-bites-is-spreading-both-in-us-and-globally

“Red meat allergy” from tick bites is spreading both in US and globally


Remember to check for ticks after your next stroll through the woods or long grasses.

Hours after savoring that perfectly grilled steak on a beautiful summer evening, your body turns traitor, declaring war on the very meal you just enjoyed. You begin to feel excruciating itchiness, pain, or even swelling that can escalate to the point of requiring emergency care.

The culprit isn’t food poisoning—it’s the fallout from a tick bite you may have gotten months earlier and didn’t even notice.

This delayed allergic reaction is called alpha-gal syndrome. While it’s commonly called the “red meat allergy,” that nickname is misleading, because alpha-gal syndrome can cause strong reactions to many products, beyond just red meat.

The syndrome is also rapidly spreading in the US and around the globe. The Centers for Disease Control and Prevention estimates as many as 450,000 people in the US may have it. And it’s carried by many more tick species than most people realize.

Map showing alpha-gal syndrome prevalence.

Cases of suspected alpha-gal syndrome based on confirmed laboratory evidence.

Credit: CDC

Cases of suspected alpha-gal syndrome based on confirmed laboratory evidence. Credit: CDC

What is alpha-gal syndrome?

Alpha-gal syndrome is actually an allergy to a sugar molecule with a tongue-twisting name: galactose-alpha-1,3-galactose, shortened to alpha-gal.

The alpha-gal sugar molecule exists in the tissues of most mammals, including cows, pigs, deer, and rabbits. But it’s absent in humans. When a big dose of alpha-gal gets into your bloodstream through a tick bite, it can send your immune system into overdrive to generate antibodies against alpha-gal. In later exposure to foods containing alpha-gal, your immune system might then launch an inappropriate allergic response.

Picture of lone star tick

A lone star tick (Amblyomma americanum). The tick can cause alpha-gal syndrome as well as carry other diseases, including ehrlichiosis, tularemia, and Southern tick-associated rash illness.

A lone star tick (Amblyomma americanum). The tick can cause alpha-gal syndrome as well as carry other diseases, including ehrlichiosis, tularemia, and Southern tick-associated rash illness. Credit: wildpixel/Getty

Often this allergy is triggered by eating red meat. But the allergy also can be set off by exposure to a range of other animal-based products, including dairy products, gelatin (think Jell-O or gummy bears), medications, and even some personal care items. The drug heparin, used to prevent blood clotting during surgery, is extracted from pig intestines, and its use has triggered a dangerous reaction in some people with alpha-gal syndrome.

Once you have alpha-gal syndrome, it’s possible to get over the allergy if you can modify your diet enough to avoid triggering another reaction for a few years and also avoid more tick bites. But that takes time and careful attention to the less obvious triggers that you might be exposed to.

Why more people are being diagnosed

As an entomologist who studies bugs and the diseases they transmit, what I find alarming is how rapidly this allergy is spreading around the globe.

Several years ago, experts thought alpha-gal syndrome was primarily limited to the Southeastern US because it was largely associated with the geographical range of the lone star tick.

photo of tick feeding on human

How a tick feeds.

However, both local and global reports have now identified many different tick species across six continents that are capable of causing alpha-gal syndrome, including the prolific black-legged tick, or deer tick, which also transmits Lyme disease.

These ticks lurk in yards and urban parks, as well as forests where they can stealthily grab onto hikers when they touch tick-infested vegetation. As tick populations boom with growing deer and human populations, the number of people with alpha-gal syndrome is escalating.

Why ticks are blamed for alpha-gal syndrome

There are a few theories on how a tick bite triggers alpha-gal syndrome and why only a small proportion of people bitten develop the allergy. To understand the theories, it helps to understand what happens as a tick starts feeding on you.

When a tick finds you, it typically looks for a warm, dark area to hide and attach itself to your body. Then its serrated teeth chew through your skin with rapid sawing motions.

As it excavates deeper into your skin, the tick deploys a barbed feeding tube, like a miniature drilling rig, and it secretes a biological cement that anchors its head into its new tunnel.

A tick’s mouth is barbed so it can stay embedded in your skin as it draws blood over hours and sometimes days.

Credit: National Institute of Allergy and Infectious Diseases

A tick’s mouth is barbed so it can stay embedded in your skin as it draws blood over hours and sometimes days. Credit: National Institute of Allergy and Infectious Diseases

Once secure, the tick activates its pumping station, injecting copious amounts of saliva containing anesthetics, blood thinners, and, sometimes, alpha-gal sugars into the wound so it can feed undetected, sometimes for days.

One theory about how a tick bite causes alpha-gal syndrome is linked to the enormous quantity of tick saliva released during feeding, which activates the body’s strong immune response. Another suggests how the skin is damaged as the tick feeds and the possible effect of the tick’s regurgitated stomach contents into the bite site are to blame. Or it may be a combination of these and other triggers. Scientists are still investigating the causes.

What an allergic reaction feels like

The allergy doesn’t begin right away. Typically, one to three months after the sensitizing tick bite, a person with alpha-gal syndrome has their first disturbing reaction.

Alpha-gal syndrome produces symptoms that range from hives or swelling to crushing abdominal pain, violent nausea, or even life-threatening anaphylactic shock. The symptoms usually start two to six hours after a person has ingested a meat product containing alpha-gal.

Due to a general lack of awareness about the allergy, however, doctors can easily miss the diagnosis. A study in 2022 found that 42 percent of US health care practitioners had never heard of alpha-gal syndrome. A decade ago, people with alpha-gal syndrome might go years before the cause of their symptoms was accurately diagnosed. Today, the diagnosis is faster in areas where doctors are familiar with the syndrome, but in many parts of the country it can still take time and multiple doctor visits.

Unfortunately, with every additional tick bite or exposure to food or products containing alpha-gal, the allergy can increase in severity.

Chart showing tick relative sizes

The lone star tick isn’t the only one that can cause alpha-gal syndrome. Black-legged ticks have also been connected to cases.

Credit: US Army

The lone star tick isn’t the only one that can cause alpha-gal syndrome. Black-legged ticks have also been connected to cases. Credit: US Army

If you think you have alpha-gal syndrome

If you suspect you may have alpha-gal syndrome, the first step is to discuss the possibility with your doctor and ask them to order a simple blood test to measure whether your immune system is reacting to alpha-gal.

If you test positive, the main strategy for managing the allergy is to avoid eating any food product from a mammal, including milk and cheese, as well as other potential triggers, such as more tick bites.

Read labels carefully. Some products contain additives such as carrageenan, which is derived from red algae and contains alpha-gal.

In extreme cases, people with alpha-gal syndrome may need to carry an EpiPen to prevent anaphylactic shock. Reputable websites, such as the CDC and alphagalinformation.org, can provide more information and advice.

Mysteries remain as alpha-gal syndrome spreads

Since alpha-gal syndrome was first formally documented in the early 2000s, scientists have made progress in understanding this puzzling condition. Researchers have connected the allergy to specific tick bites and found that people with the allergy can have a higher risk of heart disease, even without allergy symptoms.

But important mysteries remain.

Scientists are still figuring out exactly how the tick bite tricks the human immune system and why tick saliva is a trigger for only some people. With growing public interest in alpha-gal syndrome, the next decade could bring breakthroughs in preventing, diagnosing, and treating this condition.

For now, the next time you are strolling in the woods or in long grasses, remember to check for ticks on your body, wear long sleeves, long pants, and tick repellent to protect yourself from these bloodthirsty hitchhikers. If you do get bitten by a tick, watch out for odd allergic symptoms to appear a few hours after your next steak or handful of gummy bears.

Lee Rafuse Haines is associate research professor of molecular parasitology and medical entomology at University of Notre Dame.

This article is republished from The Conversation under a Creative Commons license. Read the original article.

Photo of The Conversation

The Conversation is an independent source of news and views, sourced from the academic and research community. Our team of editors work with these experts to share their knowledge with the wider public. Our aim is to allow for better understanding of current affairs and complex issues, and hopefully improve the quality of public discourse on them.

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Four radioactive wasp nests found on South Carolina nuclear facility

According to the DOE, the site produced 165 million gallons of radioactive liquid waste, which has been evaporated to 34 million gallons. The site has 51 waste tanks, eight of which have been operationally closed, with the remaining 43 in various states of the closure process.

Outside experts have been quick to point out critical information missing from the DOE’s nest report, including the absolute level of radioactivity found in the nest, the specific isotopes that were found, and the type of wasps that built the nest. Some wasps build their nests from mud, while others might use chewed-up pulp from wood.

Timothy Mousseau, a biologist at the University of South Carolina who studies organisms and ecosystems in radioactive regions, told the Times that the DOE’s explanation that the wasps gathered legacy contamination for their homes is not unreasonable. “There’s some legacy radioactive contamination sitting around in the mud in the bottom of the lakes, or, you know, here and there,” he said.

“The main concern relates to whether or not there are large areas of significant contamination that have escaped surveillance in the past,” Mousseau said. “Alternatively, this could indicate that there is some new or old radioactive contamination that is coming to the surface that was unexpected.”

The DOE report of the first wasp nest said that the nest was sprayed to kill wasps, then bagged as radioactive waste. The ground and area around where the nest had been did not have any further contamination.

In a statement to the Aiken Standard, officials working at the DOE site noted that the wasps themselves pose little risk to the community—they likely have lower contamination on them and generally don’t stray more than a few hundred yards from their nests.

However, the Times pointed out a report from 2017, when officials at SRS found radioactive bird droppings on the roof of a building at the site. Birds can carry radioactive material long distances, Mousseau said.

Four radioactive wasp nests found on South Carolina nuclear facility Read More »

idaho-has-become-the-wild-frontier-of-vaccination-policy-and-public-health

Idaho has become the wild frontier of vaccination policy and public health


Idaho charts a new path as trust in public health craters.

Some 280,000 people live in the five northernmost counties of Idaho. One of the key public officials responsible for their health is Thomas Fletcher, a retired radiologist who lives on a 160-acre farm near Sandpoint.

Fletcher grew up in Texas and moved to Idaho in 2016, looking for a place where he could live a rural life alongside likeminded conservatives. In 2022, he joined the seven-member board of health of the Panhandle Health District, the regional public health authority, and he was appointed chairman last summer.

PHD handles everything from cancer screenings to restaurant hygiene inspections, and the business of the board is often mundane, almost invisible. Then, this February, Fletcher issued a short announcement online. Parents, he wrote, should be informed of the potential harms of common childhood vaccines. It was time for the board to discuss how best to communicate those risks, rather than “withholding information contra the CDC narrative.” Fletcher invited everyone who believes in “full disclosure and transparency when providing informed consent on childhood vaccines” to attend the next monthly meeting of the board, on a Thursday afternoon.

PHD board meetings tend to be sparsely attended. This one was standing-room only—the start of a monthslong debate over vaccine safety and the question of what, exactly, it means to provide informed consent.

Versions of that debate are playing out across the United States in the aftermath of the COVID-19 pandemic, which many Americans believe was badly mismanaged. The backlash has upended longstanding norms in public health: The nation’s top health official, Robert F. Kennedy Jr., publicly questions the value of common vaccines. Prominent vaccine skeptics now sit on a key advisory committee that shapes immunization practices nationwide. Polls suggest that trust in health authorities is politically polarized — and perhaps historically low. Immunization rates are dropping across the country. And many advocates are promoting a vision of public health that’s less dependent on mandates and appeals to authority, and more deferent to individuals’ beliefs.

Much of that energy has been reflected in Kennedy’s Make American Healthy Again, or MAHA, movement. The coalition is diverse — and has sometimes fractured over vaccination issues—but often channels a long-running argument that Americans should have more freedom to choose or reject vaccines and other health measures.

The backlash against traditional health authorities, said Columbia University medical historian James Colgrove, is unprecedented in recent US history. “It’s been a very, very long time since we’ve been in a place like this,” he said.

Perhaps more than anywhere else in the country, Idaho has experienced these shifts—an ongoing experiment that shows what it looks like to put a vision of individual health freedom into practice. And places like the Panhandle Health District have become testing grounds for big questions: What happens when communities move away from widespread and mandated vaccination? And what does it mean to turn MAHA principles into local public health policy?

During a recent visit to Idaho, Kennedy described the state as “the home of medical freedom.” In April, Gov. Brad Little signed the Idaho Medical Freedom Act, which bans schools, businesses, and government agencies from requiring people to participate in medical interventions, such as mask-wearing or vaccination, in order to receive services. It’s the first legislation of its kind in the country. The bill has a carveout that keeps school vaccine requirements in place, but those requirements are already mostly symbolic: The state’s exemption policy is so broad that, as one Idaho pediatrician told Undark, “you can write on a napkin, ‘I don’t want my kids to get shots because of philosophical reasons,’ and they can go to kindergarten.” Overall, reported vaccination rates for kindergarteners in Idaho are now lower than in any other state that reported data to the federal government—especially in the Panhandle Health District, where fewer than two-thirds arrive with records showing that they are up-to-date on common shots.

“It’s really kind of like watching a car accident in slow motion,” said Ted Epperly, a physician and the CEO of Full Circle Health, which operates a network of clinics in the Boise area.

Photo of Idaho countryside

A view of Sandpoint, Idaho, which sits on the shores of Lake Pend Oreille. The city, a part of Bonner County, is served by the Panhandle Health District.

Credit: Kirk Fisher/iStock/Getty Images Plus

A view of Sandpoint, Idaho, which sits on the shores of Lake Pend Oreille. The city, a part of Bonner County, is served by the Panhandle Health District. Credit: Kirk Fisher/iStock/Getty Images Plus

Public health leaders often ascribe the low vaccination rates to the work of bad-faith actors who profit from falsehoods, to the spread of misinformation, or to failures of communication: If only leaders could better explain the benefits of vaccination, this thinking goes, more people would get shots.

In interviews and public statements, health freedom advocates in Idaho describe a far deeper rift: They do not believe that public health institutions are competent or trustworthy. And restoring that trust, they argue, will require radical changes.

Fletcher, for his part, describes himself as an admirer of RFK Jr. and the Make America Healthy Again movement. With the recent appointment of a new member, he said, MAHA supporters now hold a majority on the board, where they are poised to reimagine public health work in the district.

Local public health

In the US, public health is mostly local. Agencies like the Centers for Disease Control and Prevention conduct research and issue influential recommendations. But much of the actual power rests with the country’s thousands of state, local, and tribal public health authorities—with institutions, in other words, like the Panhandle Health District, and with leaders like Fletcher and his fellow PHD board of health member Duke Johnson.

Johnson says he grew up in Coeur d’Alene, Idaho, in the 1960s, the descendant of homesteaders who arrived in the 19th century. He attended medical school at the University of California, Los Angeles and eventually returned to Idaho, where he runs a family medical practice and dietary supplement business in the town of Hayden.

In Idaho, health boards are appointed by elected county commissioners. The commissioners of Kootenai County gave Johnson the nod in July 2023. Johnson took the role, he said, in order to restore trust in a medical system that he characterized as beholden to rigid dogmas and protocols rather than independent thinking.

In interviews and public statements, health freedom advocates in Idaho describe a far deeper rift: They do not believe that public health institutions are competent or trustworthy.

Last winter, Johnson took a tour of one of the PHD clinics. Among other services, it provides routine childhood immunizations, especially for families with limited access to health care. As is standard in pediatrics practices, the clinic hands out flyers from the CDC that review the potential side effects of common vaccines, including “a very remote chance” of severe outcomes. Johnson was unimpressed with the CDC writeup. “I thought: This isn’t completely covering all of the risk-benefit ratio,” Johnson said. He felt families could be better informed about what he sees as the substantial risks of common shots.

Johnson is an outlier among physicians. The overwhelming majority of laboratory scientists, epidemiologists, and pediatricians who have devoted their lives to the study of childhood disease say that routine immunizations are beneficial, and that serious side effects are rare. Large-scale studies have repeatedly failed to find purported links between the measles-mumps-rubella, or MMR, vaccine and autism, or to identify high rates of severe side effects for other routine childhood immunizations. The introduction of mass vaccinations in the US in the 1950s and 1960s was followed by dramatic declines in the rates of childhood diseases like polio and measles that once killed hundreds of American children each year, and sent tens of thousands more to the hospital. Similar declines have been recorded around the world.

Children can suffer side effects from common shots like the MMR vaccine, ranging from mild symptoms like a rash or fever to rare fatal complications. Public health agencies and vaccine manufacturers study and track those side effects. But today, many Americans simply do not trust that those institutions are being transparent about the risks of vaccination.

Johnson shares some of those concerns. The website for his clinic, Heart of Hope Health, describes offering services for “injection-injured” patients, encouraging them to receive a $449 heart scan, and advertises “no forced masks or vaccinations.” (During a PHD board meeting, Johnson said that one of his own children suffered an apparent bad reaction to a vaccine many years ago.) “The lack of trust in established medicine is probably 10 times bigger than the people at Harvard Medical School realize,” Johnson told Undark during an evening phone call, after a long day seeing patients. Top medical institutions have brilliant scientists on staff, he continued. But, he suggested, those experts have lost touch with how they’re seen by much of the public: “I think sometimes you can spend so much time talking to the same people who agree with you that you’re not reaching the people on the street who are the ones who need the care. And I’m in the trenches.”

Many public health experts agree that restoring trust is an urgent priority, and they are convinced that it will come through better communication, a reduction in the circulation of misinformation, and a re-building of relationships. Johnson and others in the health freedom movement frequently adopt the language of restoring trust, too. But for them, the process tends to mean something different: an overhaul of public health institutions and a frank accounting of their perceived failures.

At the board meeting in February, Johnson laid out the proposal for a change in policy: What if the board wrote up its own document for parents, explaining the evidence behind specific vaccines, and laying out the risks and benefits of the shots? The goal, he told Undark, was “to make sure that the people that we’re responsible for in our in our district can make an informed decision.”

Fletcher was also hoping to change the way PHD communicated about vaccines. Why did a push for informed consent appeal to him? “I can summarize the answer to that question with one word,” Fletcher said. “COVID.”

Nobody’s telling me what to do

Idaho is ideologically diverse, with blue pockets in cities like Boise, and texture to its overwhelming Republican majority. (Latter-Day Saint conservatives in East Idaho, for example, may not always be aligned with government-skeptical activists clustered in the north.) Parts of the state have a reputation for libertarian politics—and for resistance to perceived excesses of government authority.

People came West because “they wanted to get out to a place where nobody would tell them what to do,” said Epperly, the Boise-area physician and administrator. That libertarian ethos, he said, can sometimes translate into a skepticism of things like school vaccination requirements, even as plenty of Idahoans, including Epperly, embrace them.

Like all US states, Idaho technically requires vaccination for children to attend school. But it is relatively easy to opt out of the requirement. In 2021, Idaho lawmakers went further, instructing schools to be proactive and notify parents they had the option to claim an exemption.

“Idaho has some of the strongest languages in the US when it comes to parental rights and vaccine exemptions,” the vaccine-skeptical advocacy group Health Freedom Idaho wrote in 2021. In the 2024–2025 school year, more than 15 percent of kindergarten parents in the state claimed a non-medical exemption, the highest percentage, by far, of the states that reported data.

The pandemic, Epperly and other Idaho health care practitioners said, accelerated many of these trends. In his view, much of that backlash was about authority and control. “The pandemic acted as a catalyst to increase this sense of governmental overreach, if you will,” he said. The thinking, he added, was: “‘How dare the federal government mandate that we wear masks, that we socially distance, that we hand-wash?’”

Recently, advocates have pushed to remove medical mandates in the state altogether through the Idaho Medical Freedom Act, which curtails the ability of local governments, businesses, and schools to impose things like mask mandates or vaccine requirements.

The author of the original bill is Leslie Manookian, an Idaho activist who has campaigned against what she describes as the pervasive dangers of some vaccines, and who leads a national nonprofit, the Health Freedom Defense Fund. In testimony to an Idaho state Senate committee this February, she described feeling shocked by mitigation measures during the COVID-19 pandemic. “Growing up, I could have never, ever imagined that Idaho would become a place that locked its people down, forced citizens to cover their faces, stand on floor markers 6 feet apart, or produce proof of vaccination in order to enter a venue or a business,” Manookian told the senators.

“Idaho has some of the strongest languages in the US when it comes to parental rights and vaccine exemptions.”

Where some public health officials saw vital interventions for the public’s well-being, Manookian saw a form of government overreach, based on scant evidence. Her home state, she argued, could be a leader in building a post-COVID vision of public health. “Idaho wants to be the shining light on the Hill, that leads the way for the rest of the nation in understanding that we and we alone are sovereign over our bodies, and that our God-given rights belong to us and to no one else,” Manookian said during the hearing. A modified version of the bill passed both houses with large majorities, and became law in April.

Epperly, like many physicians and public health workers in the state, has watched these changes with concern. The family medicine specialist grew up in Idaho. During the pandemic, he was a prominent local figure advocating for masking and COVID-19 vaccinations. When the pandemic began, he had been serving on the board of the Boise-area Central District Health department for more than a decade. Then, in 2021, Ada County commissioners declined to renew his appointment, selecting a physician and vocal opponent of COVID-19 vaccines instead.

A transformative experience

For Thomas Fletcher, the Panhandle Health District board of health chair, the experience of the pandemic was transformative. Fletcher has strong political views; he moved away from Texas, in part, over concerns that the culture there was growing too liberal, and out of a desire to live in a place that was, as he put it, “more representative of America circa 1950.” But before the pandemic, he said, although he was a practicing physician, he rarely thought about public health.

Then COVID-19 arrived, and it felt to him that official messaging was disconnected from reality. In early 2020, the World Health Organization said that COVID-19 was not an airborne virus. (There’s a scientific consensus today that it actually is.) Prominent scientists argued that it was a conspiracy theory to say that COVID-19 emerged from a lab. (The issue is still hotly debated, but many scientists now acknowledge that a lab leak is a real possibility.) The World Health Organization appeared to indicate that the fatality rate of COVID-19 was upwards of 3 percent. (It’s far lower.)

Many people today understand these reversals as the results of miscommunications, evolving evidence, or good-faith scientific error. Fletcher came to believe that Anthony Fauci—a member of the White House Coronavirus Task Force during the pandemic—and other public health leaders were intentionally, maliciously misleading the public. Fletcher reads widely on the platform Substack, particularly writers who push against the medical establishment, and he concluded that COVID-19 vaccines were dangerous, too—a toxic substance pushed by pharma, and backed knowingly by the medical elite. “They lied to us,” he said.

That shift ultimately led the retired physician to question foundational ideas in his field. “Once you realize they’re lying to us, then you ask the question, ‘Well, where else are they lying?’” Fletcher said during one of several lengthy phone conversations with Undark. “I was a card-carrying allopathic physician,” he said. “I believed in the gospel.” But he soon began to question the evidence behind cholesterol medication, and then antidepressants, and then the childhood vaccination schedule.

In 2022, lawmakers in Bonner County appointed Fletcher to the board of health. Last year, he took the helm of the board, which oversees an approximately 90-person agency with a $12 million budget.

“As Chairman of Panhandle Health, I feel a certain urge to restore the trust—public trust in public health—because that trust has been violated,” he said.

The informed consent measure seemed like one way to get there.

Conversations around informed consent

On a February afternoon, in a conference room at the health district office in Hayden, a few dozen attendees and board members gathered to discuss vaccination policy and informed consent in the district.

During the lengthy public comment periods, members of the public spoke about their experiences with vaccination. One woman described witnessing the harms of diseases that have been suppressed by vaccination, noting that her mother has experienced weakness in her limbs as the result of a childhood polio infection. Several attendees reported firsthand encounters with what they understood to be vaccine side effects; one cited rising autism rates. They wanted parents to hear more about those possibilities before getting shots.

In response, some local pediatrics providers insisted they already facilitated informed consent, through detailed conversations with caregivers. They also stressed the importance of routine shots; one brought up the measles outbreak emerging in Texas, which would go on to be implicated in the deaths of two unvaccinated children.

“Once you realize they’re lying to us, then you ask the question, ‘Well, where else are they lying?’”

Johnson, defending the measure, proposed a document that listed both pros and cons for vaccination. The PHD Board, he argued, “would have a much better chance of providing good information than the average person on the Internet.”

The conversation soon bogged down over what, exactly, the document should look like. “If the vote is yay or nay for informed consent, I’m all in with two hands,” said board member Jessica Jameson, an anesthesiologist who ultimately voted against the measure. “But my concern is that we have to be very careful about the information we present and the way that it’s presented.” The board members, she added, were neither “the subject matter experts nor the stakeholders,” and studies that seemed strong on first-glance could be subject to critique.

Marty Williams, a nurse practitioner in Coeur d’Alene who works in pediatrics, had heard about the meeting that morning, as materials about the measure circulated online.

Williams is a former wildland firefighter, a father of five, and a Christian; he snowboards and bowhunts in his free time, and speaks with the laid-back affect of someone who has spent years coaching anxious parents through childhood scrapes and illnesses. A document associated with the proposal looked to him less like an attempt at informed consent, and more like a bid to talk parents out of giving their children immunizations. “If you read this, you would be like, ‘Well, I would never vaccinate my child,’” he recalled. “It was beyond informed consent. It seemed to be full of bias.”

He and his practice partner, Jeanna Padilla, canceled appointments in order to attend the meeting and speak during a public comment period. “The thought of it coming from our public health department made me sick,” Williams said. “We’re in the business of trying to prevent disease, and I had a strong feeling that this was going to bring more fear onto an already anxiety-provoking subject.” The issue felt high-stakes to him: That winter, he had seen more cases of pertussis, a vaccine-preventable illness, than at any point in his 18-year career.

Williams has always encountered some parents who are hesitant about vaccination. But those numbers began to rise during the COVID-19 pandemic. Trust in public health was dropping, and recommendations to vaccinate children against COVID-19, in particular, worried him. “Is this going to push people over the edge, where they just withdraw completely from vaccines?” he wondered at the time. Something did shift, he said: “We have families that historically have vaccinated their children, and now they have a new baby, and they’re like, ‘Nope, we’re not doing it. Nope, nope, nope.’”

In his practice, Williams described a change in how he’s approached parents. “I don’t say, ‘Well, you know, it’s time for Junior’s two months shots. Here’s what we’re going to do.’ I don’t approach it that way anymore, because greater than 40 or 50 percent of people are going to say, ‘Well, no, I’m not doing vaccines. And they get defensive right away,’” he said. Instead, he now opens up a conversation, asking families whether they’ve thought about vaccination, answering their questions, providing resources, talking about his personal experiences treating illness—even inviting them to consider the vaccine schedules used in Denmark or Sweden, which recommend shots for fewer diseases, if they are adamant about not following CDC guidelines.

The approach can be effective, he said, but also time-consuming and draining. “It’s emotional for me too, because there’s a piece of this that being questioned every single day in regards to the standard of care, as if you’re harming children,” he said.

“If you read this, you would be like, ‘Well, I would never vaccinate my child.’ It was beyond informed consent. It seemed to be full of bias.”

Williams doubts his comments at the February meeting achieved much. “I was shocked by what I was hearing, because it was so one-sided,” he said. What seemed to be missing, he said, was an honest account of the alternatives: “There was no discussion of, OK, then, if we don’t vaccinate children, what is our option? How else are we going to protect them from diseases that our grandparents dealt with that we don’t have to deal with in this country?”

The board punted: They’d discuss the issue again down the road.

This isn’t new

Versions of this debate have played out across Idaho—and across the country — since the end of COVID-19’s emergency phase. In an apparent national first, one Idaho health district banned COVID-19 vaccines altogether. In Louisiana, Surgeon General Ralph Abraham told public health departments to stop recommending specific vaccines. “Government should admit the limitations of its role in people’s lives and pull back its tentacles from the practice of medicine,” Abraham and his deputy wrote in a statement explaining the decision. “The path to regaining public trust lies in acknowledging past missteps, refocusing on unbiased data collection, and providing transparent, balanced information for people to make their own health decisions.”

In several states, Republican lawmakers have moved to make it easier for people to opt out of vaccines. Not all those efforts have been successful: In West Virginia this past March, for example, the Republican-dominated legislature rejected a bill that would have made it easier to obtain exemptions. Keith Marple, a Republican lawmaker who voted against the measure, cited his personal experiences with people who had been left disabled by polio. “West Virginia needs to look after its children,” he said, according to the news site West Virginia Watch.

In an apparent national first, one Idaho health district banned COVID-19 vaccines altogether.

In Idaho, like many states, vaccination rates have dropped. In the 2023-2024 school year, a bit more than 65 percent of kindergarten families in the Panhandle Health District furnished records showing they’ve received the MMR vaccine and five other common immunizations, down from just over 69 percent in the 2019-2020 school year. (State officials note that some children may have received shots, but their parents did not submit the paperwork to prove it.) Such figures, infectious disease modelers say, leave the area vulnerable to outbreaks of measles and other illnesses.

During an interview with Undark earlier this year, Sarah Leeds, who directs the immunization program for the Idaho Department of Health and Welfare, noted her colleagues across the country are reporting resistance to their work. “Sometimes it’s hard when you might be feeling like people think we’re the villain,” she said. “But I know our team and our leadership knows we do good work, and it’s based on sound science, and it’s important work for the community. And we just keep that at the front of our minds.”

When the board reconvened in early March, more advocates for the informed consent policy came out to back it. Among them was Rick Kirschner, a retired naturopathic doctor, author, and speaker. (His best-known book is titled “Dealing With People You Can’t Stand.”) Kirschner lived for decades in Ashland, Oregon. Early in 2020, he began to diverge from his neighbors over COVID-19 policies. He and his wife visited north Idaho that summer, and bought a home there weeks later. Compared to pandemic-conscious Oregon, it felt like a different reality. That Thanksgiving, he said during a recent Zoom interview, they attended a celebration “with 10 families and all their kids running around. It just was, ‘Oh, we’re Americans again.’ And it was just terrific.”

At the meeting in March, several people said that it was necessary to restore trust in public health institutions. But what, exactly, did that mean? Kirschner argued that it required more information, including more detailed accountings of all the ways public health interventions like vaccination could cause harm, and more detail on where the scientific literature falls short. “Denying information risks backfiring when risks that were hidden become known and trust in authorities craters,” he said during the hearing.

“I find that people are smarter than these public health people give them credit for,” he said during his call with Undark. There was a tendency in public health, he felt, to treat people like cattle. “The mindset of public health is, ‘They’re dummies, and we need to direct them and to what we think is in their interest,’” he said.

Others at the meeting pushed back against suggestions that public health workers and clinicians were not already providing detailed information to patients. “It’s not like Panhandle Health is against informed consent, or does not have that as part of the process” said Peggy Cuvala, a member of the board. Cuvala has personal experience with the issue: She spent more than three decades as a public health nurse and nurse practitioner with the Panhandle Health District. “I would never force anyone into vaccination,” she said in a phone interview.

Cuvala is well aware that vaccine side effects happen—one of her own children, she said, suffered an adverse reaction to a shot—but she’s also seen transformative benefits. For years, she had to fill out reports on cases of Haemophilus influenzae that had caused meningitis in young children, including one case in which an infant died. Then a vaccine arrived. “Within a year of that vaccine coming out, I didn’t have to do those reports anymore,” she told Undark.

Cuvala describes herself as feeling perplexed by the recent direction of the board. “I think protecting and promoting the health and well being of the residents in North Idaho is critical,” she wrote in an email. “This work should be directed by the board collectively without political bias.”

During the meeting, legal questions came up, too: What were the liability implications of drawing up a custom PHD vaccine safety document?

In a previous meeting, Fletcher had pushed for a document that just gave basic details on the duration and scope of the randomized controlled trials that common vaccines had been subjected to. Such information, he argued, would demonstrate how poorly vetted the shots were—and show how they could be dangerous, even fatal. After that, he said in an interview, it was the parent’s choice. “If some mom wants her kid to get it, fine, give it to him,” Fletcher said. The ultimate arbiter of who was correct would be the brutal process of natural selection: “Let Darwin figure it out.”

In the March meeting, the board voted against creating a subcommittee to explore how to draft the document. “It’s dead,” said Fletcher during a phone call in early May.

A matter of trust

The discussion around the informed consent measure, though, was not entirely gone. On a Saturday morning in early May, the board held a lengthy public planning session at a government building in Coeur d’Alene. During a visioning session, attendees put stickers on pieces of paper next to words describing opportunities for the district. At the bottom of the page, someone wrote, in large, all-caps: “TRUST.”

Kirschner spoke again at the meeting, urging the board to revive the measure. So did a handful of other attendees, including Ron Korn, a county commissioner.

In a short interview at the meeting, PHD spokesperson Katherine Hoyer expressed some uncertainty about what substantive differences, precisely, the measure would offer over what’s already taking place in clinics. “What they’re proposing is that we provide patients with information on medical practices and vaccines,” she said. “That is happening.”

Fletcher sees opportunities ahead. In July, the board unanimously reelected him as chair. And, he said, he has a new ally in the push for an informed consent policy. Jessica Jameson, one of the board members who opposed the measure, recently resigned. Fletcher described her successor, a naturopathic doctor who was appointed to the board last month, as aligned with the MAHA movement. That brings the total MAHA-aligned members, by his count, to four — securing a majority on the seven-member board. “My plan is unfolding just as I wanted,” he said during a call in late July.

During an earlier conversation, Fletcher had reflected on the strange position of RFK Jr., who is perched atop the Department of Health and Human Services, which is staffed by many of the people he spent his career opposing. “He has hundreds of thousands of employees; 99.99 percent of them think he’s full of shit,” Fletcher said. Fletcher, in some ways, has his own miniature version of that problem: An antagonist of institutional public health, overseeing a public health organization.

The precise informed consent measure, he acknowledged, may not come to pass. But the debate itself has merit, he said: “Even if we lose, whatever lose means, even if we don’t make any positive forward motion — you never know. Every time you talk about this, you maybe change someone’s sentiment. You maybe move things forward a little bit. Which is why I do it.”

Fletcher’s role is small. But, he suggested, added together, the cumulative efforts of local politicking could amount to a revolution. “Robert Kennedy needs as many people putting their oar in the water and stroking in the same direction,” Fletcher said. “He can’t do it alone. So if there are 10,000 Thomas Fletchers out there, all going in the same direction, then maybe we can have hope.”

Rajah Bose contributed reporting from Idaho.

This article was originally published on Undark. Read the original article.

Idaho has become the wild frontier of vaccination policy and public health Read More »

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Five children see HIV viral loads vanish after taking antiretroviral drugs


The first widespread success in curing HIV may come from children, not adults.

An ARV tablet being held in Kisumu, Kenya, on April 24, 2025 Credit: Michel Lunaga/Getty

For years, Philip Goulder has been obsessed with a particularly captivating idea: In the hunt for an HIV cure, could children hold the answers?

Starting in the mid-2010s, the University of Oxford pediatrician and immunologist began working with scientists in the South African province of KwaZulu-Natal, with the aim of tracking several hundred children who had acquired HIV from their mothers, either during pregnancy, childbirth, or breastfeeding.

After putting the children on antiretroviral drugs early in their lives to control the virus, Goulder and his colleagues were keen to monitor their progress and adherence to standard antiretroviral treatment, which stops HIV from replicating. But over the following decade, something unusual happened. Five of the children stopped coming to the clinic to collect their drugs, and when the team eventually tracked them down many months later, they appeared to be in perfect health.

“Instead of their viral loads being through the roof, they were undetectable,” says Goulder. “And normally HIV rebounds within two or three weeks.”

In a study published last year, Goulder described how all five remained in remission, despite having not received regular antiretroviral medication for some time, and in one case, up to 17 months. In the decadeslong search for an HIV cure, this offered a tantalizing insight: that the first widespread success in curing HIV might not come in adults, but in children.

At the recent International AIDS Society conference held in Kigali, Rwanda, in mid-July, Alfredo Tagarro, a pediatrician at the Infanta Sofia University Hospital in Madrid, presented a new study showing that around 5 percent of HIV-infected children who receive antiretrovirals within the first six months of life ultimately suppress the HIV viral reservoir—the number of cells harboring the virus’s genetic material—to negligible levels. “Children have special immunological features which makes it more likely that we will develop an HIV cure for them before other populations,” says Tagarro.

His thoughts were echoed by another doctor, Mark Cotton, who directs the children’s infectious diseases clinical research unit at the University of Stellenbosch, Cape Town.

“Kids have a much more dynamic immune system,” says Cotton. “They also don’t have any additional issues like high blood pressure or kidney problems. It makes them a better target, initially, for a cure.”

According to Tagarro, children with HIV have long been “left behind” in the race to find a treatment that can put HIV-positive individuals permanently into remission. Since 2007, 10 adults are thought to have been cured, having received stem cell transplants to treat life-threatening blood cancer, a procedure which ended up eliminating the virus. Yet with such procedures being both complex and highly risky—other patients have died in the aftermath of similar attempts—it is not considered a viable strategy for specifically targeting HIV.

Instead, like Goulder, pediatricians have increasingly noticed that after starting antiretroviral treatment early in life, a small subpopulation of children then seem able to suppress HIV for months, years, and perhaps even permanently with their immune system alone. This realization initially began with certain isolated case studies: the “Mississippi baby” who controlled the virus for more than two years without medication, and a South African child who was considered potentially cured having kept the virus in remission for more than a decade. Cotton says he suspects that between 10 and 20 percent of all HIV-infected children would be capable of controlling the virus for a significant period of time, beyond the typical two to three weeks, after stopping antiretrovirals.

Goulder is now launching a new study to try and examine this phenomenon in more detail, taking 19 children in South Africa who have suppressed HIV to negligible levels on antiretrovirals, stopping the drugs, and seeing how many can prevent the virus from rebounding, with the aim of understanding why. To date, he says that six of them have been able to control the virus without any drugs for more than 18 months. Based on what he’s seen so far, he has a number of ideas about what could be happening. In particular, it appears that boys are more likely to better control the virus due to a quirk of gender biology to do with the innate immune system, the body’s first-line defense against pathogens.

“The female innate immune system both in utero and in childhood is much more aggressive than the male equivalent when it encounters and senses viruses like HIV,” says Goulder. “Usually that’s a good thing, but because HIV infects activated immune cells, it actually seems to make girls more vulnerable to being infected.”

In addition, Goulder notes that because female fetuses share the same innate immune system as their mothers, the virus transmitted to them is an HIV strain that has become resistant to the female innate immune response.

There could also be other explanations for the long-lasting suppression seen in some children. In some cases, Goulder has observed that the transmitted strain of HIV has been weakened through needing to undergo changes to circumvent the mother’s adaptive immune response, the part of the immune system which learns to target specific viruses and other pathogens. He has also noted that male infants experience particularly large surges of testosterone in the first six months of life—a period known as “mini-puberty”—which can enhance their immune system in various ways that help them fight the virus.

Such revelations are particularly tantalizing as HIV researchers are starting to get access to a far more potent toolbox of therapeutics. Leading the way are so-called bNAbs, or broadly neutralizing antibodies, which have the ability to recognize and fight many different strains of HIV, as well as stimulating the immune system to destroy cells where HIV is hiding. There are also a growing number of therapeutic vaccines in development that can train the immune system’s T cells to target and destroy HIV reservoirs. Children tend to respond to various vaccines better than adults, and Goulder says that if some children are already proving relatively adept at controlling the virus on the back of standard antiretrovirals, these additional therapeutics could give them the additional assistance they need to eradicate HIV altogether.

In the coming years, this is set to be tested in several clinical trials. Cotton is leading the most ambitious attempt, which will see HIV-infected children receive a combination of antiretroviral therapy, three bNAbs, and a vaccine developed by the University of Oxford, while in a separate trial, Goulder is examining the potential of a different bNAb together with antiretrovirals to see whether it can help more children achieve long-term remission.

“We think that adding the effects of these broadly neutralizing antibodies to antiretrovirals will help us chip away at what is needed to achieve a cure,” says Goulder. “It’s a little bit like with leukemia, where treatments have steadily improved, and now the outlook for most children affected is incredibly good. Realistically in most cases, curing HIV probably requires a few hits from different angles, impacting the way that the virus can grow, and tackling it with different immune responses at the same time to essentially force it into a cul-de-sac that it can’t escape from.”

Children are also being viewed as the ideal target population for an even more ambitious experimental treatment, a one-time gene therapy that delivers instructions directing the body’s own muscle cells to produce a continuous stream of bNAbs, without the need for repeated infusions. Maurico Martins, an associate professor at the University of Florida, who is pioneering this new approach, feels that it could represent a particularly practical strategy for low-income countries where HIV transmission to children is particularly rife, and mothers often struggle to keep their children on repeated medication.

“In regions like Uganda or parts of South Africa where this is very prevalent, you could also give this therapy to a baby right after birth as a preventative measure, protecting the newborn child against acquisition of HIV through breastfeeding and maybe even through sexual intercourse later in life,” says Martins.

While Martins also hopes that gene therapy could benefit HIV-infected adults in future, he feels it has more of a chance of initially succeeding in children because their nascent immune systems are less likely to launch what he calls an anti-drug response that can destroy the therapeutic bNAbs.

“It’s very difficult for most antibodies to recognize the HIV envelope protein because it’s buried deep within a sugar coat,” says Martins. “To overcome that, these bNAbs carry a lot of mutations and extensions to their arms which allow them to penetrate that sugar coat. But the problem then is that they’re often viewed by your own immune system as foreign, and it starts making these anti-bNAb antibodies.”

But when Martins tested the therapy in newborn rhesus macaques, it was far more effective. “We found that the first few days or two weeks after birth comprised a sort of sweet spot for this gene therapy,” he says. “And that’s why this could really work very well in treating and preventing pediatric HIV infections.”

Like many HIV scientists, Martins has run into recent funding challenges, with a previous commitment from the National Institutes of Health to support a clinical trial of the novel therapy in HIV-infected children being withdrawn. However, he is hoping that the trial will still go ahead. “We’re now talking with the Gates Foundation to see whether they can sponsor it,” he says.

While children still comprise the minority of overall HIV infections, being able to cure them may yield further insights that help with the wider goal of an overall curative therapy.

“We can learn a lot from them because they are different,” says Goulder. “I think we can learn how to achieve a cure in kids if we continue along this pathway, and from there, that will have applications in adults as well.”

This story originally appeared on wired.com.

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Wired.com is your essential daily guide to what’s next, delivering the most original and complete take you’ll find anywhere on innovation’s impact on technology, science, business and culture.

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Under RFK Jr, CDC skips study on vaccination rates, quietly posts data on drop

Vaccination rates among the country’s kindergartners have fallen once again, with coverage of the measles, mumps, and rubella (MMR) vaccination dropping from 92.7 percent in the 2023–2024 school year to 92.5 percent in 2024–2025. The percentage changes are small across the board, but they represent thousands of children and an ongoing downward trend that makes the country more vulnerable to outbreaks.

In the latest school year, an estimated 286,000 young children were not fully protected against measles. At the same time, the country has seen numerous explosive measles outbreaks, with case counts in 2025 already higher than any other year since the highly infectious disease was declared eliminated in 2000. In fact, the case count is at a 33-year high.

The latest small decline is one in a series that is eroding the nation’s ability to keep bygone infectious diseases at bay. In the 2019–2020 school year, 95 percent of kindergartners were protected against measles and other serious childhood diseases, such as polio. That 95 percent coverage is the target that health experts say prevents an infectious disease from spreading in a community. But amid the pandemic, vaccination rates fell, dropping to 93.9 percent MMR coverage in the 2020–2021 year, and have kept creeping downward.

Anti-vaccine era

At the height of the pandemic, some slippage in immunization coverage could be blamed on disrupted access. But anti-vaccine sentiments and misinformation are clearly playing a large role as vaccination continues to decline and access has largely resumed. For the 2024–2025 school year, nonmedical exemptions for childhood vaccinations once again hit a new high. These are exemptions driven by ideology and have risen with the influence of anti-vaccine voices, including current health secretary and fervent anti-vaccine advocate Robert F. Kennedy Jr.

Under RFK Jr, CDC skips study on vaccination rates, quietly posts data on drop Read More »

senate-confirms-cdc-director-as-top-fda-official-resigns-under-political-pressure

Senate confirms CDC director as top FDA official resigns under political pressure

As of yesterday, Susan Monarez is in and Vinay Prasad is out among top federal health officials.

In a 51–47 vote along party lines, the Senate confirmed Monarez as the director of the Centers for Disease Control and Prevention. She is the first nominee for CDC director to be required to get Senate confirmation, following a 2022 law requiring it. She is also the first person to serve in the role without a medical degree since 1953.

Monarez has a PhD in microbiology and immunology and previously served as the deputy director for the Advanced Research Projects Agency for Health (ARPA-H) under the Biden administration. Monarez quietly helmed the CDC as acting director from January to March of this year but stepped down as required when Donald Trump nominated her for the permanent role. Before that, Trump had nominated Dave Weldon, but the nomination was abandoned over concerns that his anti-vaccine views would torpedo his Senate confirmation.

In contrast, Monarez aligns with the evidence-based public health community and has support from health experts. Jennifer Nuzzo, director of the Pandemic Center at the Brown University School of Public Health, told NPR that she has known Monarez professionally for more than a decade. “She’s a loyal, hardworking civil servant who leads with evidence and pragmatism and has been dedicated to improving the health of Americans for the entirety of her career,” Nuzzo said of Monarez.

Similarly, Georges Benjamin, executive director of the American Public Health Association, told the outlet that Monarez “values science, is a solid researcher, and has a history of being a good manager. We’re looking forward to working with her.”

It remains to be seen how Monarez will balance evidence-based public health guidance with the ideologically driven choices of health secretary and fervent anti-vaccine advocate Robert F. Kennedy Jr.

Senate confirms CDC director as top FDA official resigns under political pressure Read More »

“it’s-shocking”:-massive-raw-milk-outbreak-from-2023-finally-reported

“It’s shocking”: Massive raw milk outbreak from 2023 finally reported


The outbreak occurred in 2023–2024, but little information had been shared about it.

On October 20, 2023, health officials in the County of San Diego, California, put out a press release warning of a Salmonella outbreak linked to raw (unpasteurized) milk. Such an outbreak is not particularly surprising; the reason the vast majority of milk is pasteurized (heated briefly to kill germs) is because milk can easily pick up nasty pathogens in the farmyard that can cause severe illnesses, particularly in children. It’s the reason public health officials have long and strongly warned against consuming raw milk.

At the time of the press release, officials in San Diego County had identified nine residents who had been sickened in the outbreak. Of those nine, three were children, and all three children had been hospitalized.

On October 25, the county put out a second press release, reporting that the local case count had risen to 12, and the suspected culprit—raw milk and raw cream from Raw Farm LLC—had been recalled. The same day, Orange County’s health department put out its own press release, reporting seven cases among its residents, including one in a 1-year-old infant.

Both counties noted that the California Department of Public Health (CDPH), which had posted the recall notice, was working on the outbreak, too. But it doesn’t appear that CDPH ever followed up with its own press release about the outbreak. The CDPH did write social media posts related to the outbreak: One on October 26, 2023, announced the recall; a second on November 30, 2023, noted “a recent outbreak” of Salmonella cases from raw milk but linked to general information about the risks of raw milk; and a third on December 7, 2023, linked to general information again with no mention of the outbreak.

But that seems to be the extent of the information at the time. For anyone paying attention, it might have seemed like the end of the story. But according to the final outbreak investigation report—produced by CDPH and local health officials—the outbreak actually ran from September 2023 to March 2024, spanned five states, and sickened at least 171 people. That report was released last week, on July 24, 2025.

Shocking outbreak

The report was published in the Morbidity and Mortality Weekly Report, a journal run by the Centers for Disease Control and Prevention. The report describes the outbreak as “one of the largest foodborne outbreaks linked to raw milk in recent US history.” It also said that the state and local health department had issued “extensive public messaging regarding this outbreak.”

According to the final data, of the 171 people, 120 (70 percent) were children and teens, including 67 (39 percent) who were under the age of 5. At least 22 people were hospitalized, nearly all of them (82 percent) were children and teens. Fortunately, there were no deaths.

“I was just candidly shocked that there was an outbreak of 170 plus people because it had not been reported—at all,” Bill Marler, a personal injury lawyer specializing in food poisoning outbreaks, told Ars Technica in an interview. With the large number of cases, the high percentage of kids, and cases in multiple states, “it’s shocking that they never publicized it,” he said. “I mean, what’s the point?”

Ars Technica reached out to CDPH seeking answers about why there wasn’t more messaging and information about the outbreak during and soon after the investigation. At the time this story was published, several business days had passed and the department had told Ars in a follow-up email that it was still working on a response. Shortly after publication, CDPH provided a written statement, but it did not answer any specific questions, including why CDPH did not release its own press release about the state-wide outbreak or make case counts public during the investigation.

“CDPH takes its charge to protect public health seriously and works closely with all partners when a foodborne illness outbreak is identified,” the statement reads. It then referenced only the social media posts and the press releases from San Diego County and Orange County mentioned previously in this story as examples of its public messaging.

“This is pissing me off”

Marler, who represents around two dozen of the 171 people sickened in the outbreak, was one of the first people to get the full picture of the outbreak from California officials. In July of 2024, he obtained an interim report of the investigation from state health officials. At that point, they had documented at least 165 of the cases. And in December 2024, he got access to a preliminary report of the full investigation dated October 15, 2024, which identified the final 171 cases and appears to contain much of the data published in the MMWR, which has had its publication rate slowed amid the second Trump administration.

Getting that information from California officials was not easy, Marler told Ars. “There was one point in time where they wouldn’t give it to me. And I sent them a copy of a subpoena and I said, ‘you know, I’ve been working with public health for 32 years. I’m a big supporter of public health. I believe in your mission, but,’ I said, ‘this is pissing me off.'”

At that point, Marler knew that it was a multi-county outbreak and the CDPH and the state’s Department of Food and Agriculture were involved. He knew there was data. But it took threatening a subpoena to get it. “I’m like ‘OK, you don’t give it to me. I’m going to freaking drop a subpoena on you, and the court’s going to force you to give it.’ And they’re like, ‘OK, we’ll give it to you.'”

The October 15 state report he finally got a hold of provides a breakdown of the California cases. It reports that San Diego had a total of 25 cases (not just the 12 initially reported in the press releases), and Orange County had 19 (not just the seven). Most of the other 171 cases were spread widely across California, spanning 35 local health departments. Only four of the 171 cases were outside of California—one each in New Mexico, Pennsylvania, Texas, and Washington. It’s unclear how people in these states were exposed, given that it’s against federal law to sell raw milk for human consumption across state lines. But two of the four people sickened outside of California specifically reported that they consumed dairy from Raw Farm without going to California.

Of the 171 cases, 159 were confirmed cases, which were defined as being confirmed using whole genome sequencing that linked the Salmonella strain causing a person’s infection to the outbreak strain also found in raw milk samples and a raw milk cheese sample from Raw Farm. The remaining 12 probable cases were people who had laboratory-confirmed Salmonella infections and also reported consuming Raw Farm products within seven days prior to falling ill.

“We own it”

In an interview with Ars Technica, the owner and founder of Raw Farm, Mark McAfee, disputed much of the information in the MMWR study and the October 2024 state report. He claimed that there were not 171 cases—only 19 people got sick, he said, presumably referring to the 19 cases collectively reported in the San Diego and Orange County press releases in October 2023.

“We own it. It’s ours. We’ve got these 19 people,” he told Ars.

But he said he did not believe that the genomic data was accurate and that the other 140 cases confirmed with genetic sequencing were not truly connected to his farm’s products. He also doubted that the outbreak spanned many months and into early 2024. McAfee says that a single cow that had been purchased close to the start of the outbreak had been the source of the Salmonella. Once that animal had been removed from the herd by the end of October 23, subsequent testing was negative. He also outright did not accept that testing identified the Salmonella outbreak strain in the farm’s raw cheese, which was reported in the MMWR and the state report.

Overall, McAfee downplayed the outbreak and claimed that raw milk has significant health benefits, such as being a cure for asthma—a common myth among raw milk advocates that has been debunked. He rejects the substantial number of scientific studies that have refuted the variety of unproven health claims made by raw-milk advocates. (You can read a thorough run-down of raw milk myths and the data refuting them in this post by the Food and Drug Administration.) McAfee claims that he and his company are “pioneers” and that public health experts who warn of the demonstrable health risks are simply stuck in the past.

Outbreak record

McAfee is a relatively high-profile raw milk advocate in California. For example, health secretary and anti-vaccine advocate Robert F. Kennedy Jr. is reportedly a customer. Amid an outbreak of H5N1 on his farm last year, McAfee sent Ars press material claiming that McAfee “has been asked by the RFK transition team to apply for the position of ‘FDA advisor on Raw Milk Policy and Standards Development.'” But McAfee’s opinion of Kennedy has soured since then. In an interview with Ars last week, he said Kennedy “doesn’t have the guts” to loosen federal regulations on raw milk.

On his blog, Marler has a running tally of at least 11 outbreaks linked to the farm’s products.

In this outbreak, illnesses were caused by Salmonella Typhimurium, which generally causes diarrhea, fever, vomiting, and abdominal pain. In some severe cases, the infection can spread outside the gastrointestinal tract and into the blood, brain, bones, and joints, according to the CDC.

Marler noted that, for kids, infections can be severe. “Some of these kids who got sick were hospitalized for extended periods of time,” he said of the some of the cases he is representing in litigation. And those hospitalizations can lead to hundreds of thousands of dollars in medical expenses, he said. “It’s not just tummy aches.”

This post has been updated to include the response from CDPH.

Photo of Beth Mole

Beth is Ars Technica’s Senior Health Reporter. Beth has a Ph.D. in microbiology from the University of North Carolina at Chapel Hill and attended the Science Communication program at the University of California, Santa Cruz. She specializes in covering infectious diseases, public health, and microbes.

“It’s shocking”: Massive raw milk outbreak from 2023 finally reported Read More »

widely-panned-arsenic-life-paper-gets-retracted—15-years-after-brouhaha

Widely panned arsenic life paper gets retracted—15 years after brouhaha

In all, the astronomic hype was met with earth-shaking backlash in 2010 and 2011. In 2012, Science published two studies refuting the claim that GFAJ-1 incorporates arsenic atoms into its DNA. Outside scientists concluded that it is an arsenic-tolerant extremophile, but not a profoundly different life form.

Retraction

But now, in 2025, it is once again spurring controversy; on Thursday, Science announced that it is retracting the study.

Some critics, such as Redfield, cheered the move. Others questioned the timing, noting that 15 years had passed, but only a few months had gone by since The New York Times published a profile of Wolfe-Simon, who is now returning to science after being perceived as a pariah. Wolfe-Simon and most of her co-authors, meanwhile, continue to defend the original paper and protest the retraction.

In a blog post on Thursday, Science’s executive editor, Valda Vinson, and Editor-in-Chief Holden Thorp explained the retraction by saying that Science’s criteria for issuing a retraction have evolved since 2010. At the time, it was reserved for claims of misconduct or fraud but now can include serious flaws. Specifically, Vinson and Thorp referenced the criticism that the bacterium’s genetic material was not properly purified of background arsenic before it was analyzed. While emphasizing that there has been no suggestion of fraud or misconduct on the part of the authors, they wrote that “Science believes that the key conclusion of the paper is based on flawed data,” and it should therefore be retracted.

Jonathan Eisen, an evolutionary biologist at the University of California, Davis, criticized the move. Speaking with Science’s news team, which is independent from the journal’s research-publishing arm, Eisen said that despite being a critic of the 2010 paper, he thought the discussion of controversial studies should play out in the scientific literature and not rely on subjective decisions by editors.

In an eLetter attached to the retraction notice, the authors dispute the retraction, too, saying, “While our work could have been written and discussed more carefully, we stand by the data as reported. These data were peer-reviewed, openly debated in the literature, and stimulated productive research.”

One of the co-authors, Ariel Anbar, a geochemist at Arizona State University, told Nature that the study had no mistakes but that the data could be interpreted in different ways. “You don’t retract because of a dispute about data interpretation,” he said. If that were the case, “you’d have to retract half the literature.”

Widely panned arsenic life paper gets retracted—15 years after brouhaha Read More »

inventor-claims-bleach-injections-will-destroy-cancer-tumors

Inventor claims bleach injections will destroy cancer tumors


A lack of medical training isn’t stopping a man from charging $20,000 for the treatment.

Credit: Aurich Lawson | Getty Images

Xuewu Liu, a Chinese inventor who has no medical training or credentials of any kind, is charging cancer patients $20,000 for access to an AI-driven but entirely unproven treatment that includes injecting a highly concentrated dose of chlorine dioxide, a toxic bleach solution, directly into cancerous tumors.

One patient tells WIRED her tumor has grown faster since the procedure and that she suspects it may have caused her cancer to spread—a claim Liu disputes—while experts allege his marketing of the treatment has likely put him on the wrong side of US regulations. Nonetheless, while Liu currently only offers the treatment informally in China and at a German clinic, he is now working with a Texas-based former pharmaceutical executive to bring his treatment to America. They believe that the appointment of Robert F. Kennedy Jr. as US health secretary will help “open doors” to get the untested treatment—in which at least one clinic in California appears to have interest—approved in the US.

Kennedy’s Make America Healthy Again movement is embracing alternative medicines and the idea of giving patients the freedom to try unproven treatments. While the health secretary did not respond to a request for comment about Liu’s treatment, he did mention chlorine dioxide when questioned about President Donald Trump’s Operation Warp Speed during his Senate confirmation hearing in February, and the Food and Drug Administration recently removed a warning about the substance from its website. The agency says the removal was part of a routine process of archiving old pages on its site, but it has had the effect of emboldening the bleacher community.

“Without the FDA’s heavy-handed warnings, it’s likely my therapy would have been accepted for trials years earlier, with institutional partnerships and investor support,” Liu tells WIRED. He says he wrote to Kennedy earlier this year urging him to conduct more research on chlorine dioxide. “This quiet removal won’t immediately change everything, but it opens a door. If mainstream media reports on this shift, I believe it will unlock a new wave of serious [chlorine dioxide] research.”

For decades, pseudoscience grifters have peddled chlorine dioxide solutions—sold under a variety of names, such as Miracle Mineral Solution—and despite warnings and prosecutions have continued to claim the toxic substance is a “cure” for everything from HIV to COVID-19 to autism. There is no credible evidence to back up any of these claims, which critics have long labeled as nothing more than a grift.

The treatments typically involve drinking liquid chlorine dioxide on a regular basis, using solutions with concentrations of chlorine dioxide of around 3,000 parts per million (ppm), which is diluted further in water.

Liu’s treatment, however, involves a much higher concentration of chlorine dioxide—injections of several millilitres of 20,000 ppm—and, rather than drinking it, patients have it injected directly into their tumors.

I injected myself to test it

Liu claims he has injected himself with the solution more than 50 times and suffered no side effects. “This personal data point encouraged me to continue research,” he says.

Liu has been making the solution in his rented apartment in Beijing by mixing citric acid with sodium chlorite, according to an account he shared earlier this month on his Substack that revealed that a “violent explosion” occurred when he made a mistake.

“The blast blacked out my vision,” Liu wrote. “Dense clouds of chlorine dioxide burst into my face, filling my eyes, nose, and mouth. I stumbled back into the apartment, rushing to the bathroom to wash out the gas from my eyes and respiratory tract. My lungs were burning. Later, I would find 4–5 cuts on my upper thigh—shards of glass had pierced through my pants.” Liu also revealed that his 3-year-old daughter was nearby when the explosion happened.

Liu began a preclinical study on animals in 2016, before beginning to use the highly concentrated solution to treat human patients in more recent years. He claims that between China and Germany, he has treated 20 patients to date.

When asked for evidence to back up his claims of efficacy, Liu shared links to a number of preprints, which have not been peer-reviewed, with WIRED. He also shared a pitch deck for a $5 million seed round in a US-focused startup that would provide the chlorine dioxide injections.

The presentation contains a number of “case studies” of patients he has treated—including a dog—but rather than featuring detailed scientific data, the deck contains disturbing images of the patients’ tumors. The deck also contains, as evidence of the treatment’s efficacy, a screenshot of a WhatsApp conversation with a patient who was apparently treating a liver tumor with chlorine dioxide.

“Screenshots of WhatsApp chats with patients or their doctors is not evidence of efficacy, yet that is the only evidence he provides,” says Alex Morozov, an oncologist who has overseen hundreds of drug trials at multiple companies including Pfizer. “Needless to say, until appropriate studies are done and published in peer-reviewed journals, or presented at a reputable conference, no patients should be treated except in the context of clinical trials.”

WIRED spoke to a patient of Liu’s, whose descriptions of the treatment appear to undermine his claims of efficacy and raise serious questions about its safety.

“I bought the needles online and made the chlorine dioxide by myself [then] I injected it into the tumor and lymph nodes by myself,” says the patient, a Chinese national living in the UK. WIRED granted her anonymity to protect her privacy.

The patient had previously been taking oral solutions of chlorine dioxide as an alternative treatment for cancer, but, unsatisfied with the results, she contacted Liu via WhatsApp. On a spring evening last year, she took her first injection of chlorine dioxide and, she says, almost immediately suffered negative side effects.

“It was fine after the injection, but I was woken up by severe pain [like] I had never experienced in my life,” she says. “The pain lasted for three to four days.”

Despite the pain, she says, she injected herself again two months later, and a month after that she traveled to China, where Liu, despite having no medical training, injected her, using an anesthetic cream to numb the skin.

“While this act technically fell outside legal boundaries, in China, if the patient is competent and gives informed consent, such compassionate-use interventions rarely attract regulatory attention unless harm is done,” Liu tells WIRED.

Legal in China?

Experts on Chinese medical regulations tell WIRED that new treatments like Liu’s would have to meet strict conditions before they can be administered to patients. “It would have to go through the same steps in China as it does in the US, so that will involve clinical studies, getting ethics approval at the hospitals, and then the situation would have to be reviewed by the Chinese government,” Ames Gross, founder and president of Pacific Bridge Capital, tells WIRED. “I don’t think any of it sounds very legal.” The Chinese Ministry of Foreign Affairs, which handles all international press inquiries, did not respond to a request for comment.

As well as the initial pain, the chlorine dioxide injections also appear, the patient says, to have made the cancer worse.

“The tumor shrinks first, then it grows faster than before,” she says, adding: “My tumor has spread to the skin after injection. I suspect it is because the chlorine dioxide has broken the vein and the cancer cells go to the skin area.”

Liu did not agree with this assessment, instead blaming the fact that the patient had not completed the full course of four injections within a month, as he typically prescribes.

The patient says that thanks to a WeChat group that Liu set up, she is also in contact with other people who have had chlorine dioxide injections. One of the women, who is based in Shenzhen, China, had at least one injection of chlorine dioxide to treat what was described as vaginal cancer, but she says she is also suffering complications, according to screenshots of conversations reviewed by WIRED.

“After the injection, there was swelling and difficulty urinating,” the Chinese woman wrote. “It was very uncomfortable.”

Despite having injected a patient in China last August, Liu tells WIRED, he is not a licensed physician—he calls himself “an independent inventor and medical researcher.” The treatment, which he says is “designed to be administered by licensed physicians in clinical settings,” is so painful that it needs to be given under general anesthetic.

While Liu’s website says the treatment is being offered at clinics in Mexico, Brazil, and the Philippines, he tells WIRED that the treatment is currently only being offered at the CMC Rheinfelden clinic on the German-Swiss border. Liu features Dr. Wolfgang Renz from the clinic on his own website as one of his partners; the clinic itself does not advertise the treatment on its own website.

In conversations on WhatsApp shared with WIRED, a representative of the clinic named Lena told a prospective patient that it didn’t advertise the chlorine dioxide procedure because it was “not a legal treatment.” Lena later wrote that chlorine dioxide was not referenced on an invoice the clinic sent the same prospective patient because it is “not a legal treatment.” Lena also told the prospective patient that they had treated patients from France, Italy, and the US, according to a recording of a phone call shared with WIRED. One Italian woman is currently trying to raise money to fund her treatment in the German clinic on GoFundMe.

When asked about her comments, Lena told WIRED, “Either [the patient] misquoted me or my English was not very accurate. I repeatedly told [the patient] that it is not an approved therapy and therefore requires very detailed consent and special circumstances to be eligible for this treatment.” The prospective patient was told that she would need to bring documents detailing her prior treatment.

Renz did not respond to multiple requests for comment.

Lena also says that patients who have exhausted every other possible treatment have “the right to be treated with non-approved interventions under strict ethical conditions, full medical supervision, and informed patient consent.” The Federal Institute for Drugs and Medical Devices, which regulates medical products in Germany, did not respond to a request for comment, but Liu tells WIRED that German authorities are investigating a complaint about the clinic.

Expanding across the Pacific

Liu now appears laser-focused on making his treatment available in the US. Despite the lack of clinical data to back up his claims, Liu claims to have signed up over 100 US patients to take part in a proposed clinical research program. Liu shared a screenshot with WIRED including what appeared to be patients’ full names, zip codes, and the type of cancer they are suffering from. It’s unclear if any of the patients had agreed to have their information shared with a journalist.

Liu says he has recruited most of his potential patients via his own website. “Are You a U.S. Cancer Patient? Join the National Campaign to legalize a breakthrough therapy,” a popup that sometimes appears on Liu’s website reads, urging visitors to fill out a patient advocacy application to potentially become part of a clinical trial.

One of those who signed up is Sarah Jones, who has been diagnosed with stage 4 anal cancer that has metastasized to the lymph nodes. Jones, whose identity WIRED is protecting with a pseudonym, has already been treated with chemotherapy and drugs like cisplatin and paclitaxel. The chemotherapy originally caused the tumor to shrink, but it has since returned, and Jones is now seeking alternative treatments.

“I spend my days treating this disease like a job. Red light therapy, guided meditations, exercising, eating a keto-strong diet, and researching,” Jones tells WIRED. “This is how I stumbled upon Liu and his intratumoral injections.”

Despite signing up for a potential trial, Jones understands the risks but feels as if she is running out of choices. “I am extremely concerned that there are but a handful of patients and no data to speak of for this procedure,” Jones says. “I am debating all of my options and am constantly looking for anything that can help.”

This sentiment was echoed by Kevin, whose father has neck cancer and who also signed up as a potential patient for the trial. “If you’re in any cancer patient’s shoes, if you’re out of options, what else do you have to do? You either keep trying new therapies, or you die.”

Another US-based patient with untreated colon cancer who signed up on Liu’s website was informed that they should consider traveling to Germany for treatment, according to a screenshot of an email response from Liu, shared with WIRED. The email outlined that the cost would be €5,000 per injection, adding that “typically 4 injections [are] recommended.”

When the conversation moved to WhatsApp, Liu asked the patient what size the tumor was. The patient, who was granted anonymity to protect their privacy, told Liu the tumor was 3.8 centimeters, according to a screenshot of the WhatsApp conversation reviewed by WIRED.

Liu responded with inaccurate details and information that the patient did not share. Liu also referred to a rectal tumor rather than a colon tumor.

When the patient said they didn’t have the money to travel to Europe for the treatment and asked about getting it in the US, referencing the Williams Cancer Institute in Beverly Hills, California, Liu suggested contacting the clinic directly.

The clinic has indicated its interest in Liu’s unproven procedure by writing about Liu’s chlorine dioxide injection protocol on its own website and mentioned it on a post on its Facebook page. Liu tells WIRED that he has spoken to Jason Williams, director of the clinic. “He is very interested and is a pioneer in the field of intratumoral injections,” Liu says. “His clinic is fully capable of implementing my therapy.”

Neither Williams nor his colleague Nathan Goodyear, who Liu also says he spoke to, responded to repeated emails and phone calls seeking comment.

Liu also gave WIRED the names of a radiologist in California, an anesthesiologist in Seattle, and a physician in Missouri who he claims to have spoken to about providing his treatment in the US, but none of them responded to requests for comment.

The Chinese inventor did, however, appear on a livestream with two US-based doctors, Curtis Anderson, a Florida-based physician, and Mark Rosenberg, who works at the Institute for Healthy Aging. The discussion, hosted on Liu’s YouTube channel, saw the two doctors ask about which cancers to treat with the injections, how to buy chlorine dioxide, or even whether it’s possible to make it themselves.

Rosenberg and Anderson did not respond to requests for comment.

Maybe RFK Jr. will dig it?

Conducting a clinical trial of a new drug in the US requires approval from the Food and Drug Administration. Liu initially claimed to WIRED that “according to Article 37 of the Declaration of Helsinki and the US Right to Try laws, my therapy is already legally permissible in the United States.” Legal experts WIRED spoke to disagree strongly with Liu’s assertions.

“It sounds like Mr. Liu may not understand how the Right to Try Act or the Declaration of Helsinki work or how they fit within the broader context in which the FDA regulates investigational drugs,” Clint Hermes, an attorney with Bass, Berry & Sims, with extensive expertise in biomedical research, tells WIRED. “If he is under the impression that the ‘breast cancer trial’ referenced on his website is sufficient on its own to allow him to market or study his therapy in the US under right to try and/or the Declaration of Helsinki, he is mistaken.”

Even advertising the efficacy of an unproven treatment could land Liu in trouble, according to the American Health Law Association (AHLA).

“Companies cannot make claims regarding safety or efficacy until their products have been approved for marketing by the FDA,” Mary Kohler, a member of the AHLA’s Life Science leadership team, tells WIRED. “From a quick glance at the website, I see several claims that FDA’s Office of Prescription Drug Promotion (OPDP) would likely consider violative as pre-approval promotion even if this company were in trials that FDA was overseeing.”

The FDA and the Department of Health and Human Services did not respond to requests for comment.

When asked about these issues, Liu clarified that he was planning to initially conduct a 100-person “clinical research program” that would not require FDA approval, but Liu’s treatment doesn’t appear to meet any of the most common exemptions that would allow such a trial to take place, according to the FDA’s own website.

Liu also says he is working with “patient advocates” and leveraging their local connections to lobby state lawmakers in “liberty-leaning states” to allow the experimental treatment to be administered. This would appear to circumvent federal rules. Liu says that he has yet to make contact with such a lawmaker directly.

While he has no approval from US government agencies or support of a state or national lawmaker, Liu does have the full backing of Scott Hagerman, an entrepreneur and former executive with 30 years experience in the pharmaceutical industry, including a decade working at Pfizer.

“It’s an unbelievable breakthrough,” Hagerman tells WIRED, adding that he and his wife have been using oral chlorine dioxide solution “for some time” as a preventative measure rather than to treat a specific ailment.

Hagerman’s time in the pharmaceutical industry included over a decade running a company called Chemi Nutra, which has in the past received a US patent for a soy-based supplement that addresses testosterone decline in men. He also says he oversaw teams of scientists who worked on drug applications to the FDA for oncology drugs.

Hagerman retired from Chemi Nutra in 2021, and in the intervening years his comments indicate that he appears to have become entirely disillusioned with the modern pharmaceutical industry, referring to it as a “drugs cartel” and “a corrupt entity that is only profit-driven.” One of the issues Hagerman references is the COVID-19 vaccine based on mRNA technology, which he describes as a “con job” while also boosting the debunked theory that childhood vaccines are linked to increasing levels of autism reported in the population.

As a result, he sees Liu’s lack of experience as a positive.

“I would welcome the fact that he’s not a doctor, that he’s not an MD, because he’s not clouded, jaded, and biased with all kinds of misguidance that would push them the wrong way,” Hagerman says, adding, “I’d like to help him establish some network here in the US, because obviously the US is where the action is.” Hagerman says he is “100 percent sure” that there would be investors willing to fund the development of this treatment.

When asked about a timeline to have this procedure legally available in the US, Hagerman said he hopes it could be achieved before the end of 2025. Liu, however, thinks it could take slightly longer, saying that he believes clinical trials will begin in 2026.

This story originally appeared on wired.com.

Photo of WIRED

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Inventor claims bleach injections will destroy cancer tumors Read More »

anti-vaccine-group-founded-by-rfk-jr-sues-rfk-jr.-over-vaccine-task-force

Anti-vaccine group founded by RFK Jr. sues RFK Jr. over vaccine task force

Now that Kennedy has moved on to politics, stepping down from his role at Children’s Health Defense (CHD) and joining the Trump administration, CHD has not let go of the issue.

Ray Flores, senior outside counsel to CHD, filed the lawsuit, which is being funded by CHD. In it, Flores notes that on March 15, 2025, he sent Kennedy a 60-day notice about the task force issue, and Kennedy did not respond.

Overall, the lawsuit contains anti-vaccine talking points and false claims, such as that childhood vaccines have not gone through safety testing (they have). Flores justifies the lawsuit saying that, without the task force, he “and his family can’t make informed decisions in light of the onslaught of current and seemingly never-ending outbreaks.”

In a social media post from CHD on Tuesday, Flores criticized Kennedy directly. “Why is he not dealing with vaccines? This is not the Bobby we know,” he said in the posted video. “Is he being held captive in the swamp? And it kind of feels that way sometimes, doesn’t it?”

It remains unclear why Kennedy has not set up the task force. HHS did not immediately respond to a request for comment from Ars Technica.

Otherwise, Kennedy has not shied from unilaterally rolling back access to vaccines and continuing to spread anti-vaccine misinformation as the country’s top health official. His hand-selected vaccine advisory committee has already announced its intention to question the entire childhood vaccine schedule.

Potential explanations

However, there is one clear detail that could potentially explain Kennedy’s delay. The 1986 law that sets up the task force is specific about who should be on it. The task force “shall consist of the Director of the National Institutes of Health, the Commissioner of the Food and Drug Administration, and the Director of the Centers for Disease Control [and Prevention],” the law reads. Currently, the CDC has no director.

Anti-vaccine group founded by RFK Jr. sues RFK Jr. over vaccine task force Read More »

rfk-jr.-wants-to-change-program-that-stopped-vaccine-makers-from-leaving-us-market

RFK Jr. wants to change program that stopped vaccine makers from leaving US market


RFK Jr. is targeting a little-known program that underpins childhood immunizations in the US.

US Secretary of Health and Human Services Robert F. Kennedy Jr. testifies before the Senate Committee on Health, Education, Labor, and Pensions on Capitol Hill on May 20, 2025 in Washington, DC. Credit: Getty | Tasos Katopodis

This story was originally published by ProPublica.

Five months after taking over the federal agency responsible for the health of all Americans, Robert F. Kennedy Jr. wants to overhaul an obscure but vital program that underpins the nation’s childhood immunization system.

Depending on what he does, the results could be catastrophic.

In his crosshairs is the Vaccine Injury Compensation Program, a system designed to provide fair and quick payouts for people who suffer rare but serious side effects from shots—without having to prove that drugmakers were negligent. Congress created the program in the 1980s when lawsuits drove vaccine makers from the market. A special tax on immunizations funds the awards, and manufacturers benefit from legal protections that make it harder to win big-money verdicts against them in civil courts.

Kennedy, who founded an anti-vaccination group and previously accused the pharmaceutical industry of inflicting “unnecessary and risky vaccines” on children for profits, has long argued that the program removes any incentive for the industry to make safe products.

In a recent interview with Tucker Carlson, Kennedy condemned what he called corruption in the program and said he had assigned a team to overhaul it and expand who could seek compensation. He didn’t detail his plans but did repeat the long-debunked claim that vaccines cause autism and suggested, without citing any evidence, that shots could also be responsible for a litany of chronic ailments, from diabetes to narcolepsy.

There are a number of ways he could blow up the program and prompt vaccine makers to stop selling shots in the US, like they did in the 1980s. The trust fund that pays awards, for instance, could run out of money if the government made it easy for Kennedy’s laundry list of common health problems to qualify for payments from the fund.

Or he could pick away at the program one shot at a time. Right now, immunizations routinely recommended for children or pregnant women are covered by the program. Kennedy has the power to drop vaccines from the list, a move that would open up their manufacturers to the kinds of lawsuits that made them flee years ago.

Dr. Eddy Bresnitz, who served as New Jersey’s state epidemiologist and then spent a dozen years as a vaccine executive at Merck, is among those worried.

“If his unstated goal is to basically destroy the vaccine industry, that could do it,” said Bresnitz, who retired from Merck and has consulted for vaccine manufacturers. “I still believe, having worked in the industry, that they care about protecting American health, but they are also for-profit companies with shareholders, and anything that detracts from the bottom line that can be avoided, they will avoid.”

A spokesperson for PhRMA, a US trade group for pharmaceutical companies, told ProPublica in a written statement that upending the Vaccine Injury Compensation Program “would threaten continued patient access to FDA-approved vaccines.”

The spokesperson, Andrew Powaleny, said the program “has compensated thousands of claims while helping ensure the continued availability of a safe and effective vaccine supply. It remains a vital safeguard for public health and importantly doesn’t shield manufacturers from liability.”

Since its inception, the compensation fund has paid about $4.8 billion in awards for harm from serious side effects, such as life-threatening allergic reactions and Guillain-Barré syndrome, an autoimmune condition that can cause paralysis. The federal agency that oversees the program found that for every 1 million doses of vaccine distributed between 2006 and 2023, about one person was compensated for an injury.

Since becoming Health and Human Services secretary, Kennedy has turned the staid world of immunizations on its ear. He reneged on the US government’s pledge to fund vaccinations for the world’s poorest kids. He fired every member of the federal advisory group that recommends which shots Americans get, and his new slate vowed to scrutinize the US childhood immunization schedule. Measles, a vaccine-preventable disease eliminated here in 2000, roared back and hit a grim record—more cases than the US has seen in 33 years, including three deaths. When a US senator asked Kennedy if he recommended measles shots, Kennedy answered, “Senator, if I advised you to swim in a lake that I knew there to be alligators in, wouldn’t you want me to tell you there were alligators in it?”

Fed up, the American Academy of Pediatrics and other medical societies sued Kennedy last week, accusing him of dismantling “the longstanding, Congressionally-authorized, science- and evidence-based vaccine infrastructure that has prevented the deaths of untold millions of Americans.” (The federal government has yet to respond to the suit.)

Just about all drugs have side effects. What’s unusual about vaccines is that they’re given to healthy people—even newborns on their first day of life. And many shots protect not just the individuals receiving them but also the broader community by making it harder for deadly scourges to spread. The Centers for Disease Control and Prevention estimates that routine childhood immunizations have prevented more than 1.1 million deaths and 32 million hospitalizations among the generation of Americans born between 1994 and 2023.

To most people, the nation’s vaccine system feels like a solid, reliable fact of life, doling out shots to children like clockwork. But in reality it is surprisingly fragile.

There are only a handful of companies that make nearly all of the shots children receive. Only one manufacturer makes chickenpox vaccines. And just two or three make the shots that protect against more than a dozen diseases, including polio and measles. If any were to drop out, the country could find itself in the same crisis that led President Ronald Reagan to sign the law creating the Vaccine Injury Compensation Program in 1986.

Back then, pharmaceutical companies faced hundreds of lawsuits alleging that the vaccine protecting kids from whooping cough, diphtheria, and tetanus caused unrelenting seizures that led to severe disabilities. (Today’s version of this shot is different.) One vaccine maker after another left the US market.

At one point, pediatricians could only buy whooping cough vaccines from a single company. Shortages were so bad that the CDC recommended doctors stop giving booster shots to preserve supplies for the most vulnerable babies.

While Congress debated what to do, public health clinics’ cost per dose jumped 5,000 percent in five years.

“We were really concerned that we would lose all vaccines, and we would get major resurgences of vaccine-preventable diseases,” recalled Dr. Walter Orenstein, a vaccine expert who worked in the CDC’s immunization division at the time.

A Forbes headline captured the anxiety of parents, pediatricians, and public health workers: “Scared Shotless.” So a bipartisan group in Congress hammered out the no-fault system.

Today, the program covers vaccines routinely recommended for children or pregnant women once Congress approves the special tax that funds awards. (COVID-19 shots are part of a separate, often-maligned system for handling claims of harm, though Kennedy has said he’s looking at ways to add them to the Vaccine Injury Compensation Program.)

Under program rules, people who say they are harmed by covered vaccines can’t head straight to civil court to sue manufacturers. First, they have to go through the no-fault system. The law established a table of injuries and the time frame for when those conditions must have appeared in order to be considered for quicker payouts. A tax on those vaccines — now 75 cents for every disease that a shot protects against — flows into a trust fund that pays those approved for awards. Win or lose, the program, for the most part, pays attorney fees and forbids lawyers from taking a cut of the money paid to the injured.

The law set up a dedicated vaccine court where government officials known as special masters, who operate like judges, rule on cases without juries. People can ask for compensation for health problems not listed on the injury table, and they don’t have to prove that the vaccine maker was negligent or failed to warn them about the medical condition they wound up with. At the same time, they can’t claim punitive damages, which drive up payouts in civil courts, and pain and suffering payments are capped at $250,000.

Plaintiffs who aren’t satisfied with the outcome or whose cases drag on too long can exit the program and file their cases in traditional civil courts. There they can pursue punitive damages, contingency-fee agreements with lawyers and the usual evidence gathering that plaintiffs use to hold companies accountable for wrongdoing.

But a Supreme Court ruling, interpreting the law that created the Vaccine Injury Compensation Program, limited the kinds of claims that can prevail in civil court. So while the program isn’t a full liability shield for vaccine makers, its very existence significantly narrows the cases trial lawyers can file.

Kennedy has been involved in such civil litigation. In his federal disclosures, he revealed that he referred plaintiffs to a law firm filing cases against Merck over its HPV shot in exchange for a 10 percent cut of the fees if they win. After a heated exchange with Sen. Elizabeth Warren during his confirmation proceedings, Kennedy said his share of any money from those cases would instead go to one of his adult sons, who he later said is a lawyer in California. His son Conor works as an attorney at the Los Angeles law firm benefiting from his referrals. When ProPublica asked about this arrangement, Conor Kennedy wrote, “I don’t work on those cases and I’m not receiving any money from them.”

In March, a North Carolina federal judge overseeing hundreds of cases that alleged Merck failed to warn patients about serious side effects from its HPV vaccine ruled in favor of Merck; an appeal is pending.

The Vaccine Injury Compensation Program succeeded in stabilizing the business of childhood vaccines, with many more shots developed and approved in the decades since it was established. But even ardent supporters acknowledge there are problems. The program’s staff levels haven’t kept up with the caseload. The law capped the number of special masters at eight, and congressional bills to increase that have failed. An influx of adult claims swamped the system after adverse reactions to flu shots became eligible for compensation in 2005 and serious shoulder problems were added to the injury table in 2017.

The quick and smooth system of payouts originally envisioned has evolved into a more adversarial one with lawyers for the Department of Justice duking it out with plaintiffs’ attorneys, which Kennedy says runs counter to the program’s intent. Many cases drag on for years.

In his recent interview with Carlson, he described “the lawyers of the Department of Justice, the leaders of it” working on the cases as corrupt. “They saw their job as protecting the trust fund rather than taking care of people who made this national sacrifice, and we’re going to change all that,” he said. “And I’ve brought in a team this week that is starting to work on that.”

The system is “supposed to be generous and fast and gives a tie to the runner,” he told Carlson. “In other words, if there’s doubts about, you know, whether somebody’s injury came from a vaccine or not, you’re going to assume they got it and compensate them.”

Kennedy didn’t identify who is on the team reviewing the program. At one point in the interview, he said, “We just brought a guy in this week who’s going to be revolutionizing the Vaccine Injury Compensation Program.”

The HHS employee directory now lists Andrew Downing as a counselor working in Kennedy’s office. Downing for many years has filed claims with the program and suits in civil courts on behalf of clients alleging harm from shots. Last month, HHS awarded a contract for “Vaccine Injury Compensation Program expertise” to Downing’s firm, as NOTUS has reported.

Downing did not respond to a voicemail left at his law office. HHS didn’t reply to a request to make him and Kennedy available for an interview and declined to answer detailed questions about its plans for the Vaccine Injury Compensation Program. In the past, an HHS spokesperson has said that Kennedy is “not anti-vaccine—he is pro-safety.”

While it’s not clear what changes Downing and Kennedy have in mind, Kennedy’s interview with Carlson offered some insights. Kennedy said he was working to expand the program’s three-year statute of limitations so that more people can be compensated. Downing has complained that patients who have certain autoimmune disorders don’t realize their ailments were caused by a vaccine until it’s too late to file. Congress would have to change the law to allow this, experts said.

A key issue is whether Kennedy will try to add new ailments to the list of injuries that qualify for quicker awards.

In the Carlson interview, Kennedy dismissed the many studies and scientific consensus that shots don’t cause autism as nothing more than statistical trickery. “We’re going to do real science,” Kennedy said.

The vaccine court spent years in the 2000s trying cases that alleged autism was caused by the vaccine ingredient thimerosal and the shot that protects people from measles, mumps, and rubella. Facing more than 5,000 claims, the court asked a committee of attorneys representing children with autism to pick test cases that represented themes common in the broader group. In the cases that went to trial, the special masters considered more than 900 medical articles and heard testimony from dozens of experts. In each of those cases, the special masters found that the shots didn’t cause autism.

In at least two subsequent cases, children with autism were granted compensation because they met the criteria listed in the program’s injury table, according to a vaccine court decision. That table, for instance, lists certain forms of encephalopathy—a type of brain dysfunction—as a rare side effect of shots that protect people from whooping cough, measles, mumps, and rubella. In a 2016 vaccine court ruling, Special Master George L. Hastings Jr. explained, “The compensation of these two cases, thus does not afford any support to the notion that vaccinations can contribute to the causation of autism.”

Hastings noted that when Congress set up the injury table, the lawmakers acknowledged that people would get compensated for “some injuries that were not, in fact, truly vaccine-caused.”

Many disabling neurological disorders in children become apparent around the time kids get their shots. Figuring out whether the timing was coincidental or an indication that the vaccines caused the problem has been a huge challenge.

Devastating seizures in young children were the impetus for the compensation program. But in the mid-1990s, after a yearslong review of the evidence, HHS removed seizure disorder from the injury table and narrowed the type of encephalopathy that would automatically qualify for compensation. Scientists subsequently have discovered genetic mutations that cause some of the most severe forms of epilepsy.

What’s different now, though, is that Kennedy, as HHS secretary, has the power to add autism or other disorders to that injury table. Experts say he’d have to go through the federal government’s cumbersome rulemaking process to do so. He could also lean on federal employees to green-light more claims.

In addition, Kennedy has made it clear he’s thinking about illnesses beyond autism. “We have now this epidemic of immune dysregulation in our country, and there’s no way to rule out vaccines as one of the key culprits,” he told Carlson. Kennedy mentioned diabetes, rheumatoid arthritis, seizure disorders, ADHD, speech delay, language delay, tics, Tourette syndrome, narcolepsy, peanut allergies, and eczema.

President Donald Trump’s budget estimated that the value of the investments in the Vaccine Injury Compensation Program trust fund could reach $4.8 billion this year. While that’s a lot of money, a life-care plan for a child with severe autism can cost tens of millions of dollars, and the CDC reported in April that 1 in 31 children is diagnosed with autism by their 8th birthday. The other illnesses Kennedy mentioned also affect a wide swath of the US population.

Dr. Paul Offit, a co-inventor of a rotavirus vaccine and director of the Vaccine Education Center at Children’s Hospital of Philadelphia, for years has sparred with Kennedy over vaccines. Offit fears that Kennedy will use flawed studies to justify adding autism and other common medical problems to the injury table, no matter how much they conflict with robust scientific research.

“You can do that, and you will bankrupt the program,” he said. “These are ways to end vaccine manufacturing in this country.”

If the trust fund were to run out of money, Congress would have to act, said Dorit Reiss, a law professor at University of California Law San Francisco who has studied the Vaccine Injury Compensation Program. Congress could increase the excise tax on vaccines, she said, or pass a law limiting what’s on the injury table. Or Congress could abolish the program, and the vaccine makers would find themselves back in the situation they faced in the 1980s.

“That’s not unrealistic,” Reiss said.

Rep. Paul Gosar, an Arizona Republican, last year proposed the End the Vaccine Carveout Act, which would have allowed people to bypass the no-fault system and head straight to civil court. His press release for the bill—written in September, before Kennedy’s ascension to HHS secretary—quoted Kennedy saying, “If we want safe and effective vaccines, we need to end the liability shield.”

The legislation never came up for a vote. A spokesperson for the congressman said he expects to introduce it again “in the very near future.”

Renée Gentry, director of the George Washington University Law School’s Vaccine Injury Litigation Clinic, thinks it’s unlikely Congress will blow up the no-fault program. But Gentry, who represents people filing claims for injuries, said it’s hard to predict what Congress, faced with a doomsday scenario, would do.

“Normally Democrats are friends of plaintiffs’ lawyers,” she said. “But talking about vaccines on the Hill is like walking on a razor blade that’s on fire.”

Photo of ProPublica

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trump’s-claims-of-a-coca-cola-agreement-quickly-go-flat-as-nutritionists-groan

Trump’s claims of a Coca-Cola agreement quickly go flat as nutritionists groan

The cloying praise for the still-unconfirmed switch that Coca-Cola has, in fact, not announced was doused with some cold reality from Coca-Cola. While continuing not to confirm the agreement, the soda maker seemed to respond to the “artificial” bit in Fox’s post, saying that HFCS is “just a sweetener made from corn. It’s safe; it has about the same number of calories per serving as table sugar and is metabolized in a similar way by your body.”

The beverage maker also said that the American Medical Association “confirmed that HFCS is no more likely to contribute to obesity than table sugar or other full-calorie sweeteners.”

A 2008 report from the AMA concluded that “Because the composition of HFCS and sucrose are so similar, particularly on absorption by the body, it appears unlikely that HFCS contributes more to obesity or other conditions than sucrose.” Though the medical association noted a lack of research directly comparing the sweeteners.

While political critics suggest that the fizzy Coke fuss is just a distraction from the president’s ongoing Epstein file scandal, health experts are shaking their heads.

Nutrition expert Marion Nestle, professor emeritus at New York University, told Stat News that the push for cane sugar, just like the push to remove artificial dyes from processed foods, was “nutritionally hilarious.” Whether Coke is sweetened with cane sugar or HFCS, it still contains the equivalent of about 10 teaspoons of sugar per 12-ounce can and poses risks for conditions such as Type 2 diabetes and cardiovascular disease. “It’s the kind of thing that makes nutritionists roll their eyes, because it doesn’t make any difference,” Nestle said.

Trump’s claims of a Coca-Cola agreement quickly go flat as nutritionists groan Read More »