Science

eli-lilly-raises-price-of-zepbound-while-trumpeting-discount-on-starter-vials

Eli Lilly raises price of Zepbound while trumpeting discount on starter vials

Pharma misdirection —

Cost for insured patients without coverage for the drug rises from $550 to $650 a month.

An Eli Lilly & Co. Zepbound injection pen arranged in the Brooklyn borough of New York, US, on Thursday, March 28, 2024.

Enlarge / An Eli Lilly & Co. Zepbound injection pen arranged in the Brooklyn borough of New York, US, on Thursday, March 28, 2024.

Pharmaceutical giant Eli Lilly earned praise this week with an announcement that it is now selling starter dosages of its popular weight-loss drug tirzepatide (Zepbound) at a price significantly lower than before. But the cheers were short-lived as critics quickly noticed that Lilly also quietly raised the price on current versions of the drug—a move that was notably missing from the company’s press release this week.

In the past, Lilly sold Zepbound only in injectable pens with a list price of $1,060 for a month’s supply. Several dosages are available—2.5 mg, 5 mg, 7.5 mg, 10 mg, 12.5 mg, or 15 mg—and patients progressively increase their dosage until they reach a maintenance dosage. The recommended maintenance dosages are 5 mg, 10 mg, or 15 mg. The higher the dose, the more the weight loss. For instance, people using the 15 mg doses lost an average of 21 percent of their weight over 17 months in a clinical trial, while those on 5 mg doses only lost an average of 15 percent of their weight.

On Tuesday, Lilly announced that it will now sell Zepbound in vials, too. And a month’s supply of vials with the 2.5 mg doses will cost $399, while a month’s supply of 5 mg doses is priced at $549—a welcome drop from the $1,060 price tag. These prices are for a self-pay option, meaning that patients with a valid, on-label prescription can buy them directly from Lilly if they have no insurance or have insurance that does not cover the drug.

“This new option helps millions of adults with obesity access the medicine they need,” Lilly said in its announcement of the vials and their prices.

The company also included a quote from James Zervos, chief operating officer of the nonprofit Obesity Action Coalition. “Expanding coverage and affordability of treatments is vital to people living with obesity,” Zervos said. “We commend Lilly for their leadership in offering an innovative solution that brings us closer to making equitable care a reality.” Even President Biden chimed in on social media, saying he was “pleased” by the discount, though he urged drug companies to cut prices “across the board.”

“No rational reason, other than greed”

But, that wasn’t the end of the news. When Lilly released its press release, people noticed that the company had also increased the price of Zepbound pens for those who have insurance plans that don’t cover the drug. In the past, Lilly offered a “savings card” that allowed these patients to buy a month’s supply of any dosage of Zepbound pens for $550. Now the price is $650, a nearly 20 percent increase.

Lilly did not respond to Ars’ request for comment or questions about why the company increased the price for some patients.

Sen. Bernie Sanders (I-Vt.), a longtime critic of the pharmaceutical industry and their drug pricing, was quick to weigh in. He called the vial prices a “modest step forward” but noted that, even with the price reduction, millions of Americans still won’t be able to pay for the drug. At $549 a month, the price of the drug is a little over the average monthly payment for a used car, which was $523 in the first quarter of this year, according to Experian. As for the increase in pen pricing, Sanders called it “bad news.”

“In addition, Eli Lilly has still refused to lower the outrageous price of Mounjaro that Americans struggling with diabetes desperately need,” Sanders went on. “There is no rational reason, other than greed, why Mounjaro should cost $1,069 a month in the United States but just $485 in the United Kingdom and $94 in Japan.”

In May, a Senate committee report concluded that uptake of such weight-loss and diabetes drugs stands to “bankrupt our entire health care system,” given the high prices and large demand in the US. The report was produced by the Senate’s Health, Education, Labor, and Pensions (HELP) committee, which is chaired by Sanders.

Eli Lilly raises price of Zepbound while trumpeting discount on starter vials Read More »

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We can now watch Grace Hopper’s famed 1982 lecture on YouTube

Amazing Grace —

The lecture featured Hopper discussing future challenges of protecting information.

Rear Admiral Grace Hopper on Future Possibilities: Data, Hardware, Software, and People (Part One, 1982).

The late Rear Admiral Grace Hopper was a gifted mathematician and undisputed pioneer in computer programming, honored posthumously in 2016 with the Presidential Medal of Freedom. She was also very much in demand as a speaker in her later career. Hopper’s famous 1982 lecture on “Future Possibilities: Data, Hardware, Software, and People,” has long been publicly unavailable because of the obsolete media on which it was recorded. The National Archives and Records Administration (NARA) finally managed to retrieve the footage for the National Security Agency (NSA), which posted the lecture in two parts on YouTube (Part One embedded above, Part Two embedded below).

Hopper earned undergraduate degrees in math and physics from Vassar College and a PhD in math from Yale in 1930. She returned to Vassar as a professor, but when World War II broke out, she sought to enlist in the US Naval Reserve. She was initially denied on the basis of her age (34) and low weight-to-height ratio, and also because her expertise elsewhere made her particularly valuable to the war effort. Hopper got an exemption, and after graduating first in her class, she joined the Bureau of Ships Computation Project at Harvard University, where she served on the Mark I computer programming staff under Howard H. Aiken.

She stayed with the lab until 1949 and was next hired as a senior mathematician by Eckert-Mauchly Computer Corporation to develop the Universal Automatic Computer, or UNIVAC, the first computer. Hopper championed the development of a new programming language based on English words. “It’s much easier for most people to write an English statement than it is to use symbols,” she reasoned. “So I decided data processors ought to be able to write their programs in English and the computers would translate them into machine code.”

Her superiors were skeptical, but Hopper persisted, publishing papers on what became known as compilers. When Remington Rand took over the company, she created her first A-0 compiler. This early achievement would one day lead to the development of COBOL for data processors, which is still the major programming language used today.

“Grandma COBOL”

In November 1952, the UNIVAC was introduced to America by CBS news anchor Walter Cronkite as the presidential election results rolled in. Hopper and the rest of her team had worked tirelessly to input voting statistics from earlier elections and write the code that would allow the calculator to extrapolate the election results based on previous races. National pollsters predicted Adlai Stevenson II would win, while the UNIVAC group predicted a landslide for Dwight D. Eisenhower. UNIVAC’s prediction proved to be correct: Eisenhower won over 55 percent of the popular vote with an electoral margin of 442 to 89.  

Hopper retired at age 60 from the Naval Reserve in 1966 with the rank of commander but was subsequently recalled to active duty for many more years, thanks to congressional special approval allowing her to remain beyond the mandatory retirement age. She was promoted to commodore in 1983, a rank that was renamed “rear admiral” two years later, and Rear Admiral Grace Hopper finally retired permanently in 1986. But she didn’t stop working: She became a senior consultant to Digital Equipment Corporation and “goodwill ambassador,” giving public lectures at various computer-related events.

One of Hopper’s best-known lectures was delivered to NSA employees in August 1982. According to a National Security Agency press release, the footage had been preserved in a defunct media format—specifically, two 1-inch AMPEX tapes. The agency asked NARA to retrieve that footage and digitize it for public release, and NARA did so. The NSA described it as “one of the more unique public proactive transparency record releases… to date.”

Hopper was a very popular speaker not just because of her pioneering contributions to computing, but because she was a natural raconteur, telling entertaining and often irreverent war stories from her early days. And she spoke plainly, as evidenced in the 1982 lecture when she drew an analogy between using pairs of oxen to move large logs in the days before large tractors, and pairing computers to get more computer power rather than just getting a bigger computer—”which of course is what common sense would have told us to begin with.” For those who love the history of computers and computation, the full lecture is very much worth the time.

Grace Hopper on Future Possibilities: Data, Hardware, Software, and People (Part Two, 1982).

Listing image by Lynn Gilbert/CC BY-SA 4.0

We can now watch Grace Hopper’s famed 1982 lecture on YouTube Read More »

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Massive nationwide meat-linked outbreak kills 5 more, now largest since 2011

Hardy germs —

CDC implores consumers to check their fridges for the recalled meats.

Listeria monocytogenes.

Enlarge / Listeria monocytogenes.

Five more people have died in a nationwide outbreak of Listeria infections linked to contaminated Boar’s Head brand meats, the Centers for Disease Control and Prevention reported Wednesday.

To date, 57 people across 18 states have been sickened, all of whom required hospitalization. A total of eight have died. The latest tally makes this the largest listeriosis outbreak in the US since 2011, when cantaloupe processed in an unsanitary facility led to 147 Listeria infections in 28 states, causing 33 deaths, the CDC notes.

The new cases and deaths come after a massive recall of more than 7 million pounds of Boar’s Head meat products, which encompassed 71 of the company’s products. That recall was announced on July 30, which itself was an expansion of a July 26 recall of an additional 207,528 pounds of Boar’s Head products. By August 8, when the CDC last provided an update on the outbreak, the number of cases had hit 43, with 43 hospitalizations and three deaths.

In a media statement Wednesday, the CDC says the updated toll of cases and deaths is a “reminder to avoid recalled products.” The agency noted that the outbreak bacteria, Listeria monocytogenes, is a “hardy germ that can remain on surfaces, like meat slicers, and foods, even at refrigerated temperatures. It can also take up to 10 weeks for some people to have symptoms of listeriosis.” The agency recommends that people look through their fridges for any recalled Boar’s Head products, which have sell-by dates into October.

If you find any recalled meats, do not eat them, the agency warns. Throw them away or return them to the store where they were purchased for a refund. The CDC and the US Department of Agriculture also recommend that you disinfect your fridge, given the germs’ ability to linger.

L. monocytogenes is most dangerous to people who are pregnant, people age 65 years or older, and people who have weakened immune systems. In these groups, the bacteria are more likely to move beyond the gastrointestinal system to cause an invasive listeriosis infection. In older and immunocompromised people, listeriosis usually causes fever, muscle aches, and tiredness but may also cause headache, stiff neck, confusion, loss of balance, or seizures. These cases almost always require hospitalization, and 1 in 6 die. In pregnant people, listeriosis also causes fever, muscle aches, and tiredness but can also lead to miscarriage, stillbirth, premature delivery, or a life-threatening infection in their newborns.

Massive nationwide meat-linked outbreak kills 5 more, now largest since 2011 Read More »

sparks-are-flying-day-and-night-as-spacex-preps-starship-pad-to-catch-a-rocket

Sparks are flying day and night as SpaceX preps Starship pad to catch a rocket

Pretty much every day for the last couple of weeks, workers wielding welding guns and torches have climbed onto SpaceX’s Starship launch pad in South Texas to make last-minute upgrades ahead of the next test flight of the world’s largest rocket.

Livestreams of the launch site provided by LabPadre and NASASpaceflight.com have shown sparks raining down two mechanical arms extending from the side of the Starship launch tower at SpaceX’s Starbase launch site on the Gulf Coast east of Brownsville, Texas. We are publishing several views here of the welding activity with the permission of LabPadre, which runs a YouTube page with multiple live views of Starbase.

If SpaceX has its way on the next flight of Starship, these arms will close together to capture the first-stage booster, called Super Heavy, as it descends back to Earth and slows to a hover over the launch pad.

This method of rocket recovery is remarkably different from how SpaceX lands its smaller Falcon 9 booster, which has landing legs to touch down on offshore ocean-going platforms or at concrete sites onshore. Catching the rocket with large metallic arms—sometimes called “mechazilla arms” or “chopsticks”—would reduce the turnaround time to reuse the booster and simplify its design, according to SpaceX.

SpaceX has launched the nearly 400-foot-tall (121 meter) Starship rocket four times, most recently in June, when the Super Heavy booster, itself roughly 233 feet (71 meters) tall, made a pinpoint splashdown in the Gulf of Mexico just off the coast of Starbase.

On the same flight in June, the Starship upper stage flew halfway around the world and reentered the atmosphere over the Indian Ocean. The ship survived reentry and splashed down in the open ocean northwest of Australia. This flight was the first time either part of the Starship rocket made it back to Earth intact, but SpaceX didn’t recover the booster or the ship.

Doubling up

Lessons learned from the June test flight prompted SpaceX to replace thousands of heat shield tiles on the Starship vehicle for the next mission. While the ship survived reentry in June, onboard camera views showed numerous tiles ripped away from the vehicle. Last month, SpaceX test-fired engines on the booster and ship assigned to the next launch.

On August 8, SpaceX said Starship and Super Heavy were “ready to fly, pending regulatory approval” from the Federal Aviation Administration. An FAA spokesperson said the agency is evaluating SpaceX’s proposed flight profile for the next Starship test flight, when SpaceX wants to try catching the booster on the pad. This will be the first time SpaceX will try to bring the stainless-steel Super Heavy booster, as long as and wider than a Boeing 747 jumbo jet, back to a landing on land.

Sparks fly at Starbase as welders work overnight at the Starship launch pad.

Enlarge / Sparks fly at Starbase as welders work overnight at the Starship launch pad.

While the rocket appears to be ready to fly, SpaceX officials clearly believe there’s more work to do on the launch pad. Closer views revealed welders are installing structural supports, or doublers, to certain parts of the catch arms. Elsewhere on the arms, workers were seen removing and adding other unknown pieces of hardware. SpaceX hasn’t specified exactly what kind of work teams are doing on the Starship launch pad in Texas, but the focus is on beefing up hardware necessary for catching the Super Heavy booster.

All of this work is occurring during the hottest part of the year in South Texas. On most days this month, afternoon temperatures have soared into the mid-to-upper 90s Fahrenheit, with sticky humidity. A lot of the work on the catch arms has occurred at night, when temperatures drop into the lower 80s.

It’s unclear how long it will take for the FAA to approve a license for SpaceX to launch and recover the rocket on the next test flight or when SpaceX will complete the upgrades on the launch pad. Elon Musk, SpaceX’s founder and CEO, suggested earlier this month that the flight could take off by the end of August, but the condition of the launch pad and remaining tests indicate a launch is still probably at least a couple of weeks away.

Once workers finish up their tasks upgrading the pad and clearing scaffolding and cranes from the area, SpaceX will likely stack the Super Heavy booster and Starship upper stage and fill them with propellants during a full countdown rehearsal, as it has before each previous Starship launch.

Musk has signaled several times that the company will try to catch the Super Heavy booster on the next flight, which will also accelerate the Starship upper stage to nearly orbital velocity for another reentry demonstration over the Indian Ocean. Last month, SpaceX released a video teasing a catch of the booster on the next Starship flight, showing the rocket returning to Starbase with its Raptor engines firing.

Meanwhile, SpaceX has stacked a second Starship launch tower next to the existing launch pad in Texas. The company still has a lot of work to do to outfit the second launch pad before it is ready to support a Starship flight, but SpaceX could have it ready for activation sometime next year. SpaceX also plans two Starship launch pads at Cape Canaveral, Florida. All these sites will allow SpaceX to launch Starships more often. The company is also finishing a sprawling factory near the Starship factory in South Texas, just a couple of miles inland from the launch pads there.

Sparks are flying day and night as SpaceX preps Starship pad to catch a rocket Read More »

nasa-has-to-be-trolling-with-the-latest-cost-estimate-of-its-sls-launch-tower

NASA has to be trolling with the latest cost estimate of its SLS launch tower

The plague lives on —

“NASA officials informed us they do not intend to request a fixed-price proposal.”

Teams with NASA’s Exploration Ground Systems Program and primary contractor Bechtel National, Inc. continue construction on the base of the platform for the new mobile launcher at Kennedy Space Center in Florida on Wednesday, April 24, 2024.

Enlarge / Teams with NASA’s Exploration Ground Systems Program and primary contractor Bechtel National, Inc. continue construction on the base of the platform for the new mobile launcher at Kennedy Space Center in Florida on Wednesday, April 24, 2024.

NASA/Isaac Watson

NASA’s problems with the mobile launch tower that will support a larger version of its Space Launch System rocket are getting worse rather than better.

According to a new report from NASA’s inspector general, the estimated cost of the tower, which is a little bit taller than the length of a US football field with its end zones, is now $2.7 billion. Such a cost is nearly twice the funding it took to build the largest structure in the world, the Burj Khalifa, which is seven times taller.

This is a remarkable explosion in costs as, only five years ago, NASA awarded a contract to the Bechtel engineering firm to build and deliver a second mobile launcher (ML-2) for $383 million, with a due date of March 2023. That deadline came and went with Bechtel barely beginning to cut metal.

According to NASA’s own estimate, the project cost for the tower is now $1.8 billion, with a delivery date of September 2027. However the new report, published Monday, concludes that NASA’s estimate is probably too conservative. “Our analysis indicates costs could be even higher due in part to the significant amount of construction work that remains,” states the report, signed by Deputy Inspector General George A. Scott.

Bigger rocket, bigger tower

NASA commissioned construction of the launch tower—at the express direction of the US Congress—to support a larger version of the Space Launch System rocket known as Block 1B. This combines the rocket’s existing core stage with a larger and more powerful second stage, known as the Exploration Upper Stage, under development by Boeing.

The space agency expects to use this larger version of the SLS rocket beginning with the Artemis IV mission, which is intended to deliver both a crewed Orion spacecraft as well as an element of the Lunar Gateway into orbit around the Moon. This is to be the second time that astronauts land on the lunar surface as part of the Artemis Program. The Artemis IV mission has a nominal launch date of 2028, but the new report confirms the widely held assumption in the space community that such a date is unfeasible.

To make a 2028 launch date for this mission, NASA said it needs to have the ML-2 tower completed by November 2026. Both NASA and the new report agree that there is a zero percent chance of this happening. Accordingly, if the Artemis IV mission uses the upgraded version of the SLS rocket, it almost certainly will not launch until mid-2029 at the earliest.

Why have the costs and delays grown so much? One reason the report cites is Bechtel’s continual underestimation of the scope and complexity of the project.

“Bechtel vastly underestimated the number of labor hours required to complete the ML-2 project and, as a result, has incurred more labor hours than anticipated. From May 2022 to January 2024, estimated overtime hours doubled to nearly 850,000 hours, reflecting the company’s attempts to meet NASA’s schedule goals.

Difficult to hold Bechtel to account

One of the major takeaways from the new report is that NASA appears to be pretty limited in what it can do to motivate Bechtel to build the mobile launch tower more quickly or at a more reasonable price. The cost-plus contracting mechanism gives the space agency limited leverage over the contractor beyond withholding award fees. The report notes that NASA has declined to exercise an option to convert the contract to a fixed-price mechanism.

“While the option officially remains in the contract, NASA officials informed us they do not intend to request a fixed-price proposal from Bechtel,” the report states. “(Exploration Ground Systems) Program and ML-2 project management told us they presume Bechtel would likely provide a cost proposal far beyond NASA’s budgetary capacity to account for the additional risk that comes with a fixed-price contract.”

In other words, since NASA did not initially require a fixed price contract, it now sounds like any bid from Bechtel would completely blow a hole in the agency’s annual budget.

The spiraling costs of the mobile launch tower have previously been a source of frustration for NASA Administrator Bill Nelson. In 2022, after cost estimates for the ML-2 structure neared $1 billion, Nelson lashed out at the cost-plus mechanism during testimony to the US Congress.

“I believe that that is the plan that can bring us all the value of competition,” Nelson said of fixed-price contracts. “You get it done with that competitive spirit. You get it done cheaper, and that allows us to move away from what has been a plague on us in the past, which is a cost-plus contract, and move to an existing contractual price.”

The plague continues to spread.

NASA has to be trolling with the latest cost estimate of its SLS launch tower Read More »

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Tattoo ink sold on Amazon has high levels of weird and rare bacteria

Infectious ink —

The recall announcement noted that the germs “present a health concern.”

BARCELONA, SPAIN - 2021/10/02: Spanish tattoo artist Oscar Garcia works on a man, during the Expo.  Fira de Barcelona hosts the XXIV edition of the Barcelona Tattoo Expo where tattoo artists from Spain and other countries exhibit tattoos and tattoo material such as ink, needles and special machinery for tattoo work. (Photo by Ramon Costa/SOPA Images/LightRocket via Getty Images)

Enlarge / BARCELONA, SPAIN – 2021/10/02: Spanish tattoo artist Oscar Garcia works on a man, during the Expo. Fira de Barcelona hosts the XXIV edition of the Barcelona Tattoo Expo where tattoo artists from Spain and other countries exhibit tattoos and tattoo material such as ink, needles and special machinery for tattoo work. (Photo by Ramon Costa/SOPA Images/LightRocket via Getty Images)

The Food and Drug Administration has been warning for years that some tattoo inks are brimming with bacteria—a large assortment that, when injected into your skin, can cause inflammatory reactions, allergic hypersensitivity, toxic responses, and, of course, straight-up infections. And, worse yet, the labels that say the inks are sterile are not reliable.

But, a recent recall of three tattoo pigments from the same manufacturer does a good job of illustrating the FDA’s concerns. The water-based inks, all from Sierra Stain, had a bizarre array of bacteria, which were found at high levels, according to FDA testing.

One ink product—described as “Carolina Blue”—offered a microbial menagerie, with six odd species identified. They included a bacterium that often dwells in the gastrointestinal system and can inflame the mucosal lining of the intestines (Citrobacter braakii), a water-borne bacterium (Cupriavidus pauculus), and several that cause opportunistic infections (Citrobacter farmer, Achromobacter xylosoxidans, Ochrobactrum anthropi, and Pseudomonas fluorescens). These are bacteria that don’t typically go about attacking humans but will if the conditions are right, including when they find themselves inside a human with a compromised immune system.

An ink called “UV China Pink” contained an unusual soil bacterium (Curtobacterium citreum/pusillum). And an “All Purpose Black” ink puzzlingly contained Acetobacter senegalensis, a bacterium first isolated from mangos in Senegal and used for industrial vinegar production in low-income countries.

The three inks were sold nationwide through Amazon. To date, there have been no reported infections or adverse reactions linked to these inks. But the FDA notes that reactions to contaminated inks can be difficult to accurately diagnose. The infections and skin responses can look like generic rashes and allergic responses, sometimes including lesions with red papules in areas where the ink was injected, the FDA notes. However, infections from tattoo ink can leave permanent scarring.

In a study published in July in Applied and Environmental Microbiology, FDA researchers tested 75 samples of tattoo and permanent makeup inks from 14 manufacturers. Of the 75 inks, 26 (35 percent) were contaminated with a total of 34 types of bacteria, many that were possibly disease-causing. Some of the bacteria were anaerobic, meaning they don’t need oxygen to grow, suggesting they could thrive in the low-oxygen environment of skin layers. Of the 40 tattoo inks specifically, nine (22 percent) were contaminated. Among all the ink samples, 49 were labeled “sterile” and, of those, 16 (33 percent) were contaminated.

The recall announcement noted that Sierra Stain is no longer in business. While the company lists a remaining email address, it did not immediately respond to a comment request from Ars on the bacteria found in their inks.

The FDA recommends that consumers be vigilant about the quality and safety of tattoo supplies and techniques. It also encourages tattoo artists to work in professional environments that can reduce the risk of contamination.

Tattoo ink sold on Amazon has high levels of weird and rare bacteria Read More »

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More bad news for psychedelic drug company: FDA expands probe after rejection

trippy trip up —

Psychedelic drug company Lykos already slashed staff and overhauled leadership.

 President of Multidisciplinary Association for Psychedelic Studies (MAPS) Rick Doblin speaks onstage during  the 2023 Concordia Annual Summit at Sheraton New York on September 18, 2023, in New York City.

Enlarge / President of Multidisciplinary Association for Psychedelic Studies (MAPS) Rick Doblin speaks onstage during the 2023 Concordia Annual Summit at Sheraton New York on September 18, 2023, in New York City.

There’s more bad news for the company behind an experimental MDMA therapy for post-traumatic stress disorder, which the Food and Drug Administration roundly rejected earlier this month.

According to a report from The Wall Street Journal, the FDA is now expanding an investigation into clinical trials behind the experimental psychedelic therapy—even though the agency has already rejected it. Agency investigators reportedly interviewed four additional people last week, asking questions regarding whether the trials underreported side effects.

People involved in the trial have previously alleged, among other things, that ill effects, such as suicidal thoughts, went undocumented, and trial participants were discouraged from reporting them to bolster the chances of FDA approval. Overall, the MDMA trials faced crushing criticism amid the FDA’s review, with outside experts and agency advisors calling out allegations of sexual misconduct at one trial site, as well as flaws in overall trial designs, multiple sources of biases, and claims of that the company behind the therapy, Lykos, fostered a cult-like belief in psychedelics.

According to the Journal, the recent interviews were being conducted by the FDA’s Office of Regulatory Affairs, which oversees inspections, and a subdivision of that office called Biomedical Research Monitoring Program, which works to ensure the quality and integrity of data submitted to FDA. Notably, when the agency rejected MDMA, it advised Lykos to conduct a new trial.

While the FDA’s rejection and expanded investigation are bad enough for Lykos, the company announced this month that it’s laying off 75 percent of its staff and overhauling its leadership. The moves were in response to the FDA’s rejections, the company said. Additionally, a scientific journal retracted three of the company’s MDMA studies, citing “protocol violations amounting to unethical conduct” in its trials, echoing claims raised amid the FDA review.

Troubling roots

Underpinning the allegations and criticisms against Lykos is its roots in drug advocacy. Lykos is a commercial spinoff of the psychedelic advocacy nonprofit Multidisciplinary Association for Psychedelic Studies (MAPS). For decades, MAPS has worked to legalize psychedelics and research their use as potential treatments, particularly mental health conditions, including PTSD, anxiety, and substance use disorders. MAPS was founded by Rick Doblin, a longtime psychedelic activist and advocate who openly believes the use of psychedelics will lead to world peace. Amid the leadership overhaul this month, Doblin left his position on Lykos’ board.

“After 38 plus years of work, I’m profoundly saddened by the FDA decision around this critically needed therapy, but am heartened that Lykos will still move forward continuing clinical research that addresses the FDA’s questions,” Doblin said in a statement. “I can speak more freely as a public advocate by resigning from the Lykos Board. The FDA delays make it more important than ever that I work at MAPS toward developing global legal access to MDMA and other psychedelics for public benefit through MAPS’ multidisciplinary research, education, and drug policy reform.”

Lykos did not immediately respond to Ars’ request for comment on the FDA’s investigation. In a response to the Journal, a company spokesperson said that “Lykos is committed to engaging with the FDA and addressing any questions it raises.” The spokesperson also noted that the company is planning to meet with the FDA about the rejection, which it is appealing.

But, trial participants and outsiders have levied heavy criticism against the company that will likely be hard to move beyond.

“The prospect of a therapy cult guiding a suggestibility-enhancing drug through clinical trials highlights unique risks that have never been publicly discussed,” Neşe Devenot, a Johns Hopkins University senior lecturer in the university’s writing program who focuses on the issue of drugs in society, said in public comments prior to the FDA rejection. “The trials should be scrutinized as if Scientology or NXIVM had submitted a new drug application to the FDA.”

Those public comments appeared in a damning report from Institute for Clinical and Economic Review, which concluded that there was insufficient evidence to back MDMA-based therapy. According to the Journal report, Devenot was among the people interviewed by FDA investigators recently.

Lykos’ saga has been a blow to the psychedelic community in general and to many patients, particularly veterans, who have reported benefits from using MDMA to treat PTSD, a condition in desperate need of effective treatments.

Amid Lykos’ troubles, the company has brought in David Hough as senior medical advisor to oversee clinical and regulatory work. Hough is a former vice president at Johnson & Johnson, where he notably helped develop Spravato—esketamine—a compound related to ketamine that was approved for use against treatment-resistant depression in 2019.

More bad news for psychedelic drug company: FDA expands probe after rejection Read More »

one-of-the-most-adventurous-human-spaceflights-since-apollo-may-launch-tonight

One of the most adventurous human spaceflights since Apollo may launch tonight

Above and beyond —

Liftoff is set for 3: 38 am ET in Florida.

The crew of Polaris Dawn, from L to R: Scott

Enlarge / The crew of Polaris Dawn, from L to R: Scott “Kidd” Poteet, Anna Menon, Sarah Gillis, and Jared Isaacman.

Polaris Program/John Kraus

SpaceX is set to launch the 14th crewed flight on its Dragon spacecraft early on Tuesday morning—and it’s an intriguing one.

This Polaris Dawn mission, helmed and funded by an entrepreneur and billionaire named Jared Isaacman, is scheduled to lift off at 3: 38 am ET (07: 38 UTC) on Tuesday from Launch Complex 39A at Kennedy Space Center in Florida.

This is just the second free-flying Crew Dragon mission that SpaceX has flown, and like the Inspiration4 mission that came before it, Polaris Dawn will once again field an entire crew of private astronauts. Although this is a private spaceflight, it really is not a space tourism mission. Rather, it seeks to push the ball of exploration forward. Isaacman has emerged as one of the most serious figures in commercial spaceflight in recent years, spending hundreds of millions of dollars to fly into space and push forward the boundaries of what private citizens can do in space.

“The idea is to develop and test new technology and operations in furtherance of SpaceX’s bold vision to enable humankind to journey among the stars,” Isaacman said last week during a news conference ahead of Tuesday’s launch.

A novel step forward

Isaacman, chief executive of the Shift4 payments company, led the Inspiration4 mission in September 2021, which was unique because the crew consisted of himself—an experienced pilot—and three newcomers to spaceflight. Isaacman used the world’s first all-civilian spaceflight, on a private vehicle, to raise hundreds of millions of dollars for charity and expand the window of who could become an astronaut.

Yet whereas Inspiration4 felt like something of a novelty, Polaris Dawn is truly pushing the boundary of private spaceflight forward. Working closely with SpaceX, Isaacman has plotted a five-day flight that will accomplish a number of significant tasks after it launches.

During the initial hours of the spaceflight, the crew will seek to fly in a highly elliptical orbit, reaching an altitude as high as 1,400 km (870 miles) above the planet’s surface. This will be the highest Earth-orbit mission ever flown by humans and the farthest any person has flown from Earth since the Apollo Moon landings more than half a century ago. This will expose the crew to a not insignificant amount of radiation, and they will collect biological data to assess harms.

The Resilience spacecraft will then descend toward a more circular orbit about 700 km above the Earth’s surface. Assuming a launch on Tuesday, the crew will don four spacesuits on Friday and open the hatch to the vacuum of space. Then Isaacman, followed by mission specialist Sarah Gillis, will each briefly climb out of the spacecraft into space.

Isaacman’s interest in performing the first private spacewalk accelerated, by years, SpaceX’s development of these spacesuits. This really is just the first generation of the suit, and SpaceX is likely to continue iterating toward a spacesuit that has its own portable life support system (PLSS). This is the “backpack” on a traditional spacesuit that allows NASA astronauts to perform spacewalks untethered to the International Space Station.

The general idea is that, as the Starship vehicle makes the surface of the Moon and eventually Mars more accessible to more people, future generations of these lower-cost spacesuits will enable exploration and settlement. That journey, in some sense, begins with this mission’s brief spacewalks, with Isaacman and Gillis tethered to the Dragon vehicle for life support.

Sarah Gillis, a mission specialist on Polaris Dawn, is pretty darn excited about going to space.

Enlarge / Sarah Gillis, a mission specialist on Polaris Dawn, is pretty darn excited about going to space.

Polaris Program/John Kraus

Lasers and SpaceXers

Isaacman and his crew will also conduct a number of other research experiments, including trying to better understand a recently detected but major concern of space habitation, spaceflight-associated neuro-ocular syndrome. This will also be the first crewed mission to test Starlink-based laser communications in space.

Then, there is the crew. Isaacman’s close friend, retired US Air Force Col. Scott “Kidd” Poteet, will be the mission’s pilot, with Gillis and Anna Menon serving as mission specialists. Both Gillis and Menon are SpaceX engineers who worked with Isaacman during Inspiration4. Now, they’ll become the first SpaceX employees to ever go into orbit, bringing their experiences back to share with their colleagues.

This is the first of three “Polaris” missions that Isaacman is scheduled to fly with SpaceX. The plan for the second Polaris mission, also to fly on a Dragon spacecraft, has yet to be determined. But it may well employ a second-generation spacesuit based on learnings from this spaceflight. The third flight, unlikely to occur before at least 2030, will be an orbital launch aboard the company’s Starship vehicle—making Isaacman and his crew the first to fly on that rocket.

One of the most adventurous human spaceflights since Apollo may launch tonight Read More »

natgeo’s-cursed-gold-documents-rise-and-fall-of-notorious-1980s-treasure-hunter

NatGeo’s Cursed Gold documents rise and fall of notorious 1980s treasure hunter

From rags to riches—to jail —

Thompson’s expedition discovered wreck of the SS Central America, aka the “Ship of Gold.”

gold coins and gold bars scattered on the ocean floor

Enlarge / Cursed Gold: A Shipwreck Scandal documents the spectacular rise and fall of treasure hunter Tommy Thompson.

Recovery Limited Partnership Liquidating Trust

Many people dream of finding lost or hidden treasure, but sometimes realizing that dream turns out to be a nightmare. Such was the case for Tommy Thompson, an American treasure hunter who famously beat the odds to discover the location of the SS Central America shipwreck in 1988. It had been dubbed the “Ship of Gold” since it sank in 1857 laden with 30,000 pounds of gold bars and coins—collectively worth enough money to have some impact on the Panic of 1857 financial crisis.

Thompson and his team recovered significant amounts of gold and artifacts to great fanfare, with experts at the time suggesting the trove could be worth as much as $400 million. The euphoria proved short-lived. Thirty-nine insurance companies filed lawsuits, claiming the gold was rightfully theirs since the companies had paid damages for the lost gold back in the mid-19th century. Thompson eventually prevailed in 1996, when courts awarded him and his discovery team 92 percent of the gold they’d recovered.

But actually realizing profits from the gold proved challenging; In the end, Thompson sold the gold for just $52 million, almost all of which went to pay off the massive debt the project had accumulated over the ensuing years. So naturally, there were more lawsuits, this time from the investors who had financed Thompson’s expedition, accusing him of fraud. Thompson didn’t help his case when he went on the run in 2012 with his assistant, living off some $4 million in assets stashed in an offshore account.

Thompson was finally captured by US marshals in 2015 to face his investors in court. A jury awarded the investors substantial compensatory damages, and the court ordered Thompson to hand over 500 commemorative gold coins that had been minted out of some of the Central America gold to meet that judgment. Thompson claimed he had forgotten where he’d stashed them and was jailed for contempt of court until the coins had been recovered and handed over. He’s still in prison as of this writing, and the gold coins have yet to be found.

It’s quite a tale, so small wonder that National Geographic has made a riveting three-part documentary about Thompson’s spectacular rise and fall: Cursed Gold: A Shipwreck Scandal, based on the 1998 book by Gary Kinder entitled Ship of Gold in the Deep Blue SeaCursed Gold director Sam Benstead read Kinder’s book and was instantly hooked on the story. “Not only was it a hugely exciting story with many twists and turns, but it was also an emotional story, which left you pulling for Tommy and his crew,” he told Ars. “Tommy came through as an extraordinary character: eccentric, brilliant, someone willing to try things no one else had. When I discovered all the things that had happened after the book, I knew it was a story I had to tell.”

Ship of Gold

  • Engraving by J. Childs of the 1857 sinking of the SS Central America.

    Public domain/National Maritime Museum, London

  • Sonar expert Mike Williamson hard at work during production of Cursed Gold.

    National Geographic

  • John Moore is a lead designer of deep-sea robot Nemo.

    National Geographic

  • Dramatic reconstruction of crew members looking at monitors in the ship’s control room.

    National Geographic

  • Dramatic reconstruction of a crew member looking at computer screens in the ship’s control room.

    National Geographic

  • Dramatic reconstruction of sonar operator John Lettow navigating Nemo from the ship’s control room.

    National Geographic

  • Dramatic reconstruction showing Nemo descending to the seabed off the coast of North Carolina.

    National Geographic

  • Gold bars and coins on the bottom of the sea bed off the coast of North Carolina.

    Recovery Limited Partnership Liquidating Trust

  • Robotic machine recovers gold bars on the bottom of the seabed.

    Recovery Limited Partnership Liquidating Trust

  • Crew members ogle gold bars on deck after being brought up from the sea floor.

    Recovery Limited Partnership Liquidating Trust

  • Crew members looking at gold bars retrieved from the ocean floor.

    Recovery Limited Partnership Liquidating Trust

  • Journalist Dylan Taylor-Lehman looks through case files.

    National Geographic

  • Veteran US Marshal Mark Stroh lifting box of files in a dramatic reconstruction.

    National Geographic

  • Lawyer Quintin Lindsmith works on case files.

    Gold bars and coins on the bottom of the sea bed off the cost of North Carolina.

  • US Marshal Christopher Crotty waits in his car in a dramatic reconstruction.

    National Geographic

  • A case displaying the missing 500 commemorative gold coins.

    Recovery Limited Partnership Liquidating Trust

A lot has happened to Thompson since Kinder’s book was published in 1998. Benstead and his production team combed through more than 600 hours of archival footage from the original expedition, as well as over 700 pages of court transcripts. “We also consulted multiple figures who we didn’t film with but who helped inform the story,” said Benstead. “In the editing process, National Geographic’s research department, together with our team, worked diligently to do their best to bottom out every fact, every claim. In a story that is so contested, this really helped us feel confident in standing behind the resulting films.”

“One of the main challenges was in condensing an incredibly complex 30-year saga into three films,” Benstead continued. “There were many legal cases and side stories that we had to exclude or could only touch on. And there were areas of the story that were strongly disputed by different sides. Sometimes we had to make choices that didn’t fully satisfy either camp, but we did our best to remain fair to the plurality of viewpoints, while also telling a powerful story.”

The director remains in awe of the original discovery, however badly the adventure turned out. “For the guys on the boat, almost without exception, this period was one of the best times of their lives,” he said. “It was a privilege to relive their struggles and final triumph in finding the gold. I still find it remarkable that they found the SS Central America in almost two miles of water with the resources they had in the 1980s.”

The experience also instilled “a real respect for the people who shared their story with us, especially Tommy’s family members, who have had so much written about them over the years,” said Benstead. “They didn’t trust us easily, and I feel very fortunate that they took part. Whenever people share the deepest, most affecting parts of their lives with you, you walk away carrying a big responsibility. I hope that they feel we have done their side of the story justice.”

Did Benstead come to his own conclusions about whether or not Thompson committed fraud? “Different people have different viewpoints on Tommy, even amongst those on the boat, investors, lawyers, and law enforcement,” he said. “We felt it was very important to allow the series to reflect this diversity and to allow the audience to make up their own mind. My own view is that Tommy isn’t a con man, and to be in prison for approaching nine years for contempt of court feels like a sad reflection on the US justice system. But it is also the case that, albeit under immense pressure, he made certain choices (like going on the run), which contributed to his own downfall. I hope that in the coming years his achievements, which have been obscured by the legal circus, are given the recognition that they deserve.”

Cursed Gold: A Shipwreck Scandal is now streaming on Disney+ and Hulu.

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US grid adds batteries at 10x the rate of natural gas in first half of 2024

In transition —

By year’s end, 96 percent of the US’s grid additions won’t add carbon to the atmosphere.

US grid adds batteries at 10x the rate of natural gas in first half of 2024

While solar power is growing at an extremely rapid clip, in absolute terms, the use of natural gas for electricity production has continued to outpace renewables. But that looks set to change in 2024, as the US Energy Information Agency (EIA) has run the numbers on the first half of the year and found that wind, solar, and batteries were each installed at a pace that dwarfs new natural gas generators. And the gap is expected to get dramatically larger before the year is over.

Solar, batteries booming

According to the EIA’s numbers, about 20 GW of new capacity was added in the first half of this year, and solar accounts for 60 percent of it. Over a third of the solar additions occurred in just two states, Texas and Florida. There were two projects that went live that were rated at over 600 MW of capacity, one in Texas, the other in Nevada.

Next up is batteries: The US saw 4.2 additional gigawatts of battery capacity during this period, meaning over 20 percent of the total new capacity. (Batteries are treated as the equivalent of a generating source by the EIA since they can dispatch electricity to the grid on demand, even if they can’t do so continuously.) Texas and California alone accounted for over 60 percent of these additions; throw in Arizona and Nevada, and you’re at 93 percent of the installed capacity.

The clear pattern here is that batteries are going where the solar is, allowing the power generated during the peak of the day to be used to meet demand after the sun sets. This will help existing solar plants avoid curtailing power production during the lower-demand periods in the spring and fall. In turn, this will improve the economic case for installing additional solar in states where its production can already regularly exceed demand.

Wind power, by contrast, is running at a more sedate pace, with only 2.5 GW of new capacity during the first six months of 2024. And for likely the last time this decade, additional nuclear power was placed on the grid, at the fourth 1.1 GW reactor (and second recent build) at the Vogtle site in Georgia. The only other additions came from natural gas-powered facilities, but these totaled just 400 MW, or just 2 percent of the total of new capacity.

Wind, solar, and batteries are the key contributors to new capacity in 2024.

Enlarge / Wind, solar, and batteries are the key contributors to new capacity in 2024.

The EIA has also projected capacity additions out to the end of 2024 based on what’s in the works, and the overall shape of things doesn’t change much. However, the pace of installation goes up as developers rush to get their project operational within the current tax year. The EIA expects a bit over 60 GW of new capacity to be installed by the end of the year, with 37 GW of that coming in the form of solar power. Battery growth continues at a torrid pace, with 15 GW expected, or roughly a quarter of the total capacity additions for the year.

Wind will account for 7.1 GW of new capacity, and natural gas 2.6 GW. Throw in the contribution from nuclear, and 96 percent of the capacity additions of 2024 are expected to operate without any carbon emissions. Even if you choose to ignore the battery additions, the fraction of carbon-emitting capacity added remains extremely small, at only 6 percent.

Gradual shifts on the grid

Obviously, these numbers represent the peak production of these sources. Over a year, solar produces at about 25 percent of its rated capacity in the US, and wind at about 35 percent. The former number will likely decrease over time as solar becomes inexpensive enough to make economic sense in places that don’t receive as much sunshine. By contrast, wind’s capacity factor may increase as more offshore wind farms get completed. For natural gas, many of the newer plants are being designed to operate erratically so that they can provide power when renewables are under-producing.

A clearer sense of what’s happening comes from looking at the generating sources that are being retired. The US saw 5.1 GW of capacity drop off the grid in the first half of 2024, and aside from a 0.2 GW of “other,” all of it was fossil fuel-powered, including 2.1 GW of coal capacity and 2.7 GW of natural gas. The latter includes a large 1.4 GW natural gas plant in Massachusetts.

But total retirements are expected to be just 7.5 GWO this year—less than was retired in the first half of 2023. That’s likely because the US saw electricity use rise by 5 percent in the first half of 2025, based on numbers the EIA released on Friday (note that this link will take you to more recent data a month from now). It’s unclear how much of that was due to weather—a lot of the country saw heat that likely boosted demand for air conditioning—and how much could be accounted for by rising use in data centers and for the electrification of transit and appliances.

That data release includes details on where the US got its electricity during the first half of 2024. The changes aren’t dramatic compared to where they were when we looked at things last month. Still, what has changed over the past month is good news for renewables. In May, wind and solar production were up 8.4 percent compared to the same period the year before. By June, they were up by over 12 percent.

Given the EIA’s expectations for the rest of the year, the key question is likely to be whether the pace of new solar installations is going to be enough to offset the drop in production that will occur as the US shifts to the winter months.

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NASA’s Starliner decision was the right one, but it’s a crushing blow for Boeing

Falling short —

It’s unlikely Boeing can fly all six of its Starliner missions before retirement of the ISS in 2030.

A Starliner spacecraft mounted on top of an Atlas V rocket before an unpiloted test flight in 2022.

Enlarge / A Starliner spacecraft mounted on top of an Atlas V rocket before an unpiloted test flight in 2022.

Ten years ago next month NASA announced that Boeing, one of the agency’s most experienced contractors, won the lion’s share of government money available to end the agency’s sole reliance on Russia to ferry its astronauts to and from low-Earth orbit.

At the time, Boeing won $4.2 billion from NASA to complete development of the Starliner spacecraft and fly a minimum of two, and potentially up to six, operational crew flights to rotate crews between Earth and the International Space Station (ISS). SpaceX won a $2.6 billion contract for essentially the same scope of work.

A decade later the Starliner program finds itself at a crossroads after Boeing learned it will not complete the spacecraft’s first Crew Flight Test with astronauts onboard. NASA formally decided Saturday that Butch Wilmore and Suni Williams, who launched on the Starliner capsule June 5, will instead return to Earth inside a SpaceX Crew Dragon spacecraft. Put simply, NASA isn’t confident enough in Boeing’s spacecraft after it suffered multiple thrusters failures and helium leaks on the way to the ISS.

So where does this leave Boeing with its multibillion contract? Can the company fulfill the breadth of its commercial crew contract with NASA before the space station’s scheduled retirement in 2030? It now seems that there is little chance of Boeing flying six more Starliner missions without a life extension for the ISS. Tellingly, perhaps, NASA has only placed firm orders with Boeing for three Starliner flights once the agency certifies the spacecraft for operational use.

Boeing’s bottom line

Although Boeing did not make an official statement Saturday on its long-term plans for Starliner, NASA Administrator Bill Nelson told reporters he received assurances from Boeing’s new CEO, Kelly Ortberg, that the company remains committed to the commercial crew program. And it will take a significant commitment from Boeing to see it through. Under the terms of its fixed price contract with NASA, the company is on the hook to pay for any expenses to fix the thruster and helium leak problems and get Starliner flying again.

Boeing has already reported $1.6 billion in charges on its financial statements to pay for delays and cost overruns on the Starliner program. That figure will grow as the company will likely need to redesign some elements in the spacecraft’s propulsion system to remedy the problems encountered on the Crew Flight Test (CFT) mission. NASA has committed $5.1 billion to Boeing for the Starliner program, and the agency has already paid out most of that funding.

Boeing's Starliner spacecraft, seen docked at the International Space Station through the window of a SpaceX Dragon spacecraft.

Enlarge / Boeing’s Starliner spacecraft, seen docked at the International Space Station through the window of a SpaceX Dragon spacecraft.

The next step for Starliner remains unclear, and we’ll assess that in more detail later in the story. Had the Starliner test flight ended as expected, with its crew inside, NASA targeted no earlier than August 2025 for Boeing to launch the first of its six operational crew rotation missions to the space station. In light of Saturday’s decision, there’s a high probability Starliner won’t fly with astronauts again until at least 2026.

Starliner safely delivered astronauts Butch Wilmore and Suni Williams to the space station on June 6, a day after their launch from Cape Canaveral Space Force Station, Florida. But five of the craft’s 28 reaction control system thrusters overheated and failed as it approached the outpost. After the failures on the way to the space station, NASA’s engineers were concerned Starliner might suffer similar problems, or worse, when the control jets fired to guide Starliner on the trip back to Earth.

On Saturday, senior NASA leaders decided it wasn’t worth the risk. The two astronauts, who originally planned for an eight-day stay at the station, will now spend eight months on the orbiting research lab until they come back to Earth with SpaceX.

If it’s not a trust problem, is it a judgement issue?

Boeing managers had previously declared Starliner was safe enough to bring Wilmore and Williams home. Mark Nappi, Boeing’s Starliner program manager, regularly appeared to downplay the seriousness of the thruster issues during press conferences throughout Starliner’s nearly three-month mission.

So why did NASA and Boeing engineers reach different conclusions? “I think we’re looking at the data and we view the data and the uncertainty that’s there differently than Boeing does,” said Jim Free, NASA’s associate administrator, and the agency’s most senior civil servant. “It’s not a matter of trust. It’s our technical expertise and our experience that we have to balance. We balance risk across everything, not just Starliner.”

The people at the top of NASA’s decision-making tree have either flown in space before, or had front-row seats to the calamitous decision NASA made in 2003 to not seek more data on the condition of space shuttle Columbia’s left wing after the impact of a block of foam from the shuttle’s fuel tank during launch. This led to the deaths of seven astronauts, and the destruction of Columbia during reentry over East Texas. A similar normalization of technical problems, and a culture of stifling dissent, led to the loss of space shuttle Challenger in 1986.

“We lost two space shuttles as a result there not being a culture in which information could come forward,” Nelson said Saturday. “We have been very solicitous of all of our employees that if you have some objection, you come forward. Spaceflight is risky, even at its safest, and even at its most routine. And a test flight by nature is neither safe nor routine. So the decision to keep Butch and Suni aboard the International Space Station and bring the Starliner home uncrewed is the result of a commitment to safety.”

Now, it seems that culture may truly have changed. With SpaceX’s Dragon spacecraft available to give Wilmore and Williams a ride home, this ended up being a relatively straightforward decision. Ken Bowersox, head of NASA’s space operations mission directorate, said the managers polled for their opinion all supported bringing the Starliner spacecraft back to Earth without anyone onboard.

However, NASA and Boeing need to answer for how the Starliner program got to this point. The space agency approved the launch of the Starliner CFT mission in June despite knowing the spacecraft had a helium leak in its propulsion system. Those leaks multiplied once Starliner arrived in orbit, and are a serious issue on their own that will require corrective actions before the next flight. Ultimately, the thruster problems superseded the seriousness of the helium leaks, and this is where NASA and Boeing are likely to face the most difficult questions moving forward.

NASA astronauts Butch Wilmore and Suni Williams aboard the International Space Station.

Enlarge / NASA astronauts Butch Wilmore and Suni Williams aboard the International Space Station.

Boeing’s previous Starliner mission, known as Orbital Flight Test-2 (OFT-2), successfully launched in 2022 and docked with the space station, later coming back to Earth for a parachute-assisted landing in New Mexico. The test flight achieved all of its major objectives, setting the stage for the Crew Flight Test mission this year. But the spacecraft suffered thruster problems on that flight, too.

Several of the reaction control system thrusters stopped working as Starliner approached the space station on the OFT-2 mission, and another one failed on the return leg of the mission. Engineers thought they fixed the problem by introducing what was essentially a software fix to adjust timing and tolerance settings on sensors in the propulsion system, supplied by Aerojet Rocketdyne.

That didn’t work. The problem lay elsewhere, as engineers discovered during testing this summer, when Starliner was already in orbit. Thruster firings at White Stands, New Mexico, revealed a small Teflon seal in a valve can bulge when overheated, restricting the flow of oxidizer propellant to the thruster. NASA officials concluded there is a chance, however small, that the thrusters could overheat again as Starliner departs the station and flies back to Earth—or perhaps get worse.

“We are clearly operating this thruster at a higher temperature, at times, than it was designed for,” said Steve Stich, NASA’s commercial crew program manager. “I think that was a factor, that as we started to look at the data a little bit more carefully, we’re operating the thruster outside of where it should be operated at.”

NASA’s Starliner decision was the right one, but it’s a crushing blow for Boeing Read More »

nasa-not-comfortable-with-starliner-thrusters,-so-crew-will-fly-home-on-dragon

NASA not comfortable with Starliner thrusters, so crew will fly home on Dragon

Boeing is going home empty handed —

“I would say the White Sands testing did give us a surprise.”

Photos of Crew Dragon relocation on the International Space Station.

Enlarge / Crew Dragon approaches the International Space Station

NASA TV

Following weeks of speculation, NASA finally made it official on Saturday: two astronauts who flew to the International Space Station on Boeing’s Starliner spacecraft in June will not return home on that vehicle. Instead, the agency has asked SpaceX to use its Crew Dragon spacecraft to fly astronauts Butch Wilmore and Suni Williams back to Earth.

“NASA has decided that Butch and Suni will return with Crew-9 next February,” said NASA Administrator Bill Nelson at the outset of a news conference on Saturday afternoon at Johnson Space Center.

In a sign of the gravity surrounding the agency’s decision, both Nelson and NASA’s deputy administrator, Pam Melroy, attended a Flight Readiness Review meeting held Saturday in Houston. During that gathering of the agency’s senior officials, an informal “go/no go” poll was taken. Those present voted unanimously for Wilmore and Williams to return to Earth on Crew Dragon. The official recommendation of the Commercial Crew Program was the same, and Nelson accepted it.

Therefore, Boeing’s Starliner spacecraft will undock from the station early next month—the tentative date, according to a source, is September 6—and attempt to make an autonomous return to Earth and land in a desert in the southwestern United States.

Then, no earlier than September 24, a Crew Dragon spacecraft will launch with two astronauts (NASA has not named the two crew members yet) to the space station with two empty seats. Wilmore and Williams will join these two Crew-9 astronauts for their previously scheduled six-month increment on the space station. All four will then return to Earth on the Crew Dragon vehicle.

Saturday’s announcement has big implications for Boeing, which entered NASA’s Commercial Crew Program more than a decade ago and lent legitimacy to NASA’s efforts to pay private companies for transporting astronauts to the International Space Station. The company’s failure—and despite the encomiums from NASA officials during Saturday’s news conference, this Starliner mission is a failure—will affect Boeing’s future in spaceflight. Ars will have additional coverage of Starliner’s path forward later today.

Never could get comfortable with thruster issues

For weeks after Starliner’s arrival at the space station in early June, officials from Boeing and NASA expressed confidence in the ability of the spacecraft to fly Wilmore and Williams home. They said they just needed to collect a little more data on the performance of the vehicle’s reaction control system thrusters. Five of these 28 small thrusters that guide Starliner failed during the trip to the space station.

Engineers from Boeing and NASA tested the performance of these thrusters at a facility in White Sands, New Mexico, in July. Initially, the engineers were excited to replicate the failures observed during Starliner’s transit to the space station. (Replicating failures is a critical step to understanding the root cause of a hardware problem.)

However, what NASA found after taking apart the failed thrusters was concerning, said the chief of NASA’s Commercial Crew Program, Steve Stich.

“I would say the White Sands testing did give us a surprise,” Stich said Saturday. “It was this piece of Teflon that swells up and got in the flow path and causes the oxidizer to not go into the thruster the way it needs to. That’s what caused the degradation of thrust. When we saw that, I think that’s when things changed a bit for us.”

When NASA took this finding to the thruster’s manufacturer, Aerojet Rocketdyne, the propulsion company said it had never seen this phenomenon before. It was at this point that agency engineers started to believe that it might not be possible to identify the root cause of the problem in a timely manner and become comfortable enough with the physics to be sure that the thruster problem would not occur during Starliner’s return to Earth.

Thank you for flying SpaceX

The result of this uncertainty is that NASA will now turn to the other commercial crew provider, SpaceX. This is not a pleasant outcome for Boeing which, a decade ago, looked askance at SpaceX as something akin to space cowboys. I have covered the space industry closely during the last 15 years, and during most of that time Boeing was perceived by much of the industry as the blueblood of spaceflight while SpaceX was the company that was going to kill astronauts due to its supposed recklessness.

Now the space agency is asking SpaceX to, in effect, rescue the Boeing astronauts currently on the International Space Station.

It won’t be the first time that SpaceX has helped a competitor recently. In the last two years SpaceX has launched satellites for a low-Earth orbit Internet competitor, OneWeb, after Russia’s space program squeezed the company; it has launched Europe’s sovereign Galileo satellites after delays to the Ariane 6 rocket; and it has launched the Cygnus spacecraft built by NASA’s other space station cargo services provider, Northrop Grumman, multiple times. Now SpaceX will help out Boeing, a crew competitor.

After Saturday’s news conference, I asked Jim Free, NASA’s highest-ranking civil servant, what he made of the once-upstart SpaceX now helping to backstop the rest of the Western spaceflight community. Without SpaceX, after all, NASA would not have a way to get crew or cargo to the International Space Station.

“They’re flying a lot, and they’re having success,” Free said. “And you know, when they have an issue, they find a way to recover like with the second-stage issue, We set out to have two providers to take crew to station to have options, and they’ve given us the option. In the reverse, Boeing could have been out there, and we still would face the same thing if they had a systemic Dragon problem, Boeing would have to bring us back. But I can’t argue with how much they’ve flown, that’s for sure, and what they’ve flown.”

NASA not comfortable with Starliner thrusters, so crew will fly home on Dragon Read More »